Results 41 to 50 of about 1,059,053 (303)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
JMIR Research ProtocolsBackgroundMobility impairment and participation restrictions are commonly experienced by individuals with autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) and myotonic dystrophy type 1 (MD1), 2 disorders that are
Ernest Niyomwungere +7 more
doaj +1 more source
Impact of Glass Cockpit Experience on Manual Flight Skills
Journal of Aviation/Aerospace Education & Research, 2006 Modern aircraft employ a wide variety of advanced flight instrument systems that have been designed to reduce pilot workload and promote safe, efficient flight operations.
John P Young +2 more
doaj +1 more source
Task Specialization, Immigration and Wages [PDF]
Many workers with low levels of educational attainment immigrated to the United States in recent decades. Large inflows of less educated immigrants would reduce wages paid to comparably-educated native-born workers if the two groups are perfectly ...
Chad Sparber, Giovanni Peri
core +3 more sources
“I’m Here to Do Business. I’m Not Here to Play Games.” Work, Consumption, and Masculinity in \u3ci\u3eStorage Wars\u3c/i\u3e [PDF]
, 2015 This essay examines the first season of Storage Wars and suggests the program helps mediate the putative crisis in American masculinity by suggesting that traditional male skills are still essential where knowledge supplants manual labor.
Kelly, Casey R., Rademacher, Mark A.
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Exploring perceptions and attitudes towards teaching and learning manual technical drawing in a digital age [PDF]
, 2007 This paper examines the place of manual technical drawing in the 21st century by discussing the perceived value and relevance of teaching school students how to draw using traditional instruments, in a world of computer aided drafting (CAD).
McLaren, Susan Valerie
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Frontiers in Psychology, 2015 Manual rendezvous and docking (manual RVD) is a challenging space task for astronauts. Previous research showed a correlation between spatial ability and manual RVD skills among participants at early stages of training, but paid less attention to experts.
Xiaoping eDu +8 more
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Acta Psychologica, 2023 The strength and development of the relationship between mathematical and motor skills is explored across three age groups of normally developing children. The presence of this relationship is postulated in classical accounts of human development.
Venera Gashaj, Dragan Trninic
doaj +1 more source