Results 61 to 70 of about 1,059,053 (303)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Skill Training System of Manual Arc Welding [PDF]

, 2003
We propose a training system of manual arc welding by means of Mixed Reality technique. The system consists of a face-shield-like Head Mounted Display (HMD) and a virtual electrode unit. The former unit is a video-see-through HMD having almost the same shape and size as an actual face shield. Mixed image of real environmental scene and virtual objects (
Kazuhiko Kobayashi, Shinobu Ishigame, Hideo Kato   +2 more
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

MANUAL GUIDANCE IN GYMNASTICS: A CASE STUDY

Science of Gymnastics Journal, 2010
Although the use of manual guidance in gymnastics is widely spread, little is known about the effects of this technique on movement kinematics. The goal of this case study was to evaluate the effects of two manual guidance procedures on movement ...
Thomas Heinen, Pia Vinken, Patrick Ölsberg   +2 more
doaj   +1 more source

Unemployment, Skills, and the Business Cycle Since 2000 [PDF]

This paper employs reduced-form microeconometric analysis to examine how yearly changes in aggregate income and GDP growth affect the unemployment probability of individuals with varied skills in the United States.
Sparber, Chad
core   +1 more source

Manual Skill Generalization Enhanced by Negative Viscosity

Journal of Neurophysiology, 2010
Recent human-machine interaction studies have suggested that movement augmented with negative viscosity can enhance performance and can even promote better motor learning. To test this, we investigated how negative viscosity influences motor adaptation to an environment where forces acted only in one axis of motion.
Felix C, Huang, James L, Patton, Ferdinando A, Mussa-Ivaldi   +2 more
openaire   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Procedural skills workshops for primary care physicians in Israel: a comprehensive analysis

BMC Medical Education
Background Some of the most common complaints addressed by primary care physicians (PCPs) require manual procedures, such as lacerations repair, abscesses drainage, ingrown toenails removal, dry needling for myofascial pain syndrome, and Epley maneuver ...
Omer Rosenblum, Ilan Yehoshua, Limor Adler, Ori Liran   +3 more
doaj   +1 more source

Cerebral Mechanism in the Development of Skill in Manual Work

The Tohoku Journal of Experimental Medicine, 1971
The cerebral mechanism in the training process of manual work was examined by simultaneous recordings of motion analysis, EMG and EEG of the subjects in the course of acquiring skill in chain-stitching. Four phases of progress were distinguished: 1) the period of increasing speed, 2) agitation period of unrhythmic and inaccurate movement. 3) the period
Y, Hori, T, Yanase, Y, Hattori, C, Terada, S, Utsumi   +4 more
openaire   +3 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source