Results 101 to 110 of about 1,654,996 (316)

Cost-effective strategies for CAR-T cell therapy manufacturing

open access: yesMolecular Therapy: Oncology
CAR-T cell therapy has revolutionized cancer treatment, with approvals for conditions like acute B-leukemia, large B cell lymphoma (LBCL), follicular lymphoma (FL), mantle cell lymphoma (MCL), and multiple myeloma.
Luiza Abdo   +2 more
doaj   +1 more source

Jeffrey Manufacturing Company Shop View

open access: yes, 1890
Exterior view of the Jeffrey Manufacturing Company factories, Columbus, Ohio, ca. 1890. The particular use of each building is unknown.
The Jeffrey Manufacturing Company (Photographer)
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Human Factors and Ergonomics in Industry 5.0—A Systematic Literature Review

open access: yesApplied Sciences
Human-centricity, sustainability, and resilience are the core pillars of the Industry 5.0 concept. The human-centric perspective emphasizes the development of socio-technical systems designed to enhance human health, safety, and well-being while ...
Maja Trstenjak   +3 more
doaj   +1 more source

From Immigrants to Robots: The Changing Locus of Substitutes for Workers

open access: yesRSF: The Russell Sage Foundation Journal of the Social Sciences, 2019
Using numbers of industrial robots shipped to primarily manufacturing industries as a supply shock to an industry labor market, we estimate that an additional robot reduces employment by roughly two to three workers overall and by three to four workers ...
George J. Borjas, Richard B. Freeman
doaj   +1 more source

Jeffrey Manufacturing Company mine ventilation fan and employee photograph

open access: yes, 1912
A photograph of an employee of the Jeffrey Manufacturing Company in Columbus, Ohio, posing beside a mine ventilation fan manufactured by the company. The Jeffrey Manufacturing Company, also known as the Jeffrey Mining Corporate Center, was established ...
Jeffrey Manufacturing Company
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Jeffrey Manufacturing Company mortar mixer photograph

open access: yes, 1899
This photograph depicts a one-horsepower mortar mixer used during the construction of a factory building at the Jeffrey Manufacturing Company in Columbus, Ohio. Steel paddles on a long shaft in the trough were turned by the horse to mix the cement mortar.
The Jeffrey Manufacturing Company (Photographer)
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Jeffrey Manufacturing Company Water Tower

open access: yes, 1960
This is a photograph of the Jeffrey Manufacturing Company water tower in Columbus, Ohio, ca. 1960 - 1970.
The Jeffrey Manufacturing Company (Photographer)
core  

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