Results 141 to 150 of about 3,117,564 (363)

Metal Additive Manufacturing: A Review

Journal of materials engineering and performance (Print), 2014
W. Frazier
semanticscholar   +1 more source

Digital twin for smart manufacturing, A review

Sustainable Manufacturing and Service Economics, 2023
Mohsen Soori, B. Arezoo, Roza Dastres
semanticscholar   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Jeffrey Manufacturing Company Chain Shop

, 1890
This is a view of the chain shop of the Jeffrey Manufacturing Company of Columbus, Ohio, ca. 1895. All of the floor machines were powered from an overhead system of drive shafts, pulleys and belts.
The Jeffrey Manufacturing Company (Photographer)
core  

The Systems Fusion Challenge: Intelligence vs. Manufacturing in Micro Smart Factories

Systems
Micro smart factories (MSFs) represent a new way for small and medium-sized enterprises (SMEs) to build smart factories. Intelligence and manufacturing are two important dimensions of intelligent manufacturing.
Yuran Jin, Jiahui Liu, Harm-Jan Steenhuis, Elmina Homapour   +3 more
doaj   +1 more source

Manufacturing Changeability and Manufacturing as a Service

IFAC-PapersOnLine
As markets and supply chains become more volatile, rapid response to changing demands is crucial. Manufacturing as a Service (MaaS) enables quick access to manufacturing assets, while changeable manufacturing designs adaptable systems. This paper investigates how 1) manufacturing as a service may support changeability, and 2) how changeability may ...
ESLAMI, YASAMIN, Brunoe, Thomas Ditlev, da Cunha, Catherine   +2 more
openaire   +4 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Jeffrey Manufacturing Company Machine Shop

, 1890
Reproduction of a photograph depicting an interior view of the Jeffrey Manufacturing Company's machine shop in Columbus, Ohio. The original photograph was taken in 1895. With an absence of electrical lighting, the shop relied on natural light that flowed
The Jeffrey Manufacturing Company (Photographer)
core  

Manufacturing Competency from Local Clusters: Roots of the Competitive Advantage of the Chinese Electric Vehicle Battery Industry

World Electric Vehicle Journal
China’s leading development of a complete battery value chain for electric vehicles (EVs) is restructuring the global automotive sector. In contrast with the normal point of view, which emphasizes the role of industrial policy, this article argues that ...
Wei Zhao, Boy Luethje
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source