Results 111 to 120 of about 1,271,617 (289)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
A project based approach to learning for first year engineering students [PDF]
, 2008 Support for transition from Leaving Certificate and entry to college for 1st year engineering students can be difficult to achieve. This new course offers an innovative project based approach to learning for 1st years with an introduction to design to ...
Corcoran, Brian, Whelan, John
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Automatic programming of simulation models [PDF]
The concepts of software engineering were used to improve the simulation modeling environment. Emphasis was placed on the application of an element of rapid prototyping, or automatic programming, to assist the modeler define the problem specification ...
Dwan, Wen S. +3 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Assessment of the international workshop on CdS solar cells [PDF]
General problems relating to the basic understanding of CdS/Cu2S solar cell operation, to material aspects of the cell and to manufacturing methods and cell engineering are ...
Boer, K. W.
core +1 more source
Investigation of factors affecting the learning of final year advanced materials and manufacturing students [PDF]
, 2007 An investigation was recently conducted into the delivery of an Advanced Materials and Manufacturing Processes module which was presented to a sub-group of the final year engineering students at Dublin City University (DCU).
Brabazon, Dermot +2 more
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RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Nanotechnology Reviews, 2012 A novel nanotechnology laboratory experiment for a required junior/senior undergraduate engineering course, Engineering of Manufacturing Processes, is described and implemented.
Jaksic Nebojsa
doaj +1 more source