Results 41 to 50 of about 1,271,617 (289)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Microelectronics Process Engineering at San Jose State University: A Manufacturing-Oriented Interdisciplinary Degree Program [PDF]

open access: yes, 2002
San Jose State University\u27s new interdisciplinary curriculum in Microelectronics Process Engineering is described. This baccalaureate program emphasizes hands-on thin-film fabrication experience, manufacturing methods such as statistical process ...
Allen, Emily   +5 more
core   +1 more source

Virtual manufacturing: prediction of work piece geometric quality by considering machine and set-up [PDF]

open access: yes, 2011
Lien vers la version éditeur: http://www.tandfonline.com/doi/full/10.1080/0951192X.2011.569952#.U4yZIHeqP3UIn the context of concurrent engineering, the design of the parts, the production planning and the manufacturing facility must be considered ...
D'ACUNTO, Alain   +2 more
core   +7 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Tutorials for Integrating CAD/CAM in Engineering Curricula

open access: yesEducation Sciences, 2018
This article addresses the issue of educating engineering students with the knowledge and skills of Computer-Aided Design and Manufacturing (CAD/CAM). In particular, three carefully designed tutorials—cutting tool offsetting, tool-path generation ...
AMM Sharif Ullah, Khalifa H. Harib
doaj   +1 more source

Hydrogels for Tissue Engineering: Addressing Key Design Needs Toward Clinical Translation

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
While the soft mechanics and tunable cell interactions facilitated by hydrogels have attracted significant interest in the development of functional hydrogel-based tissue engineering scaffolds, translating the many positive results observed in the lab ...
Fei Xu   +9 more
doaj   +1 more source

Engineering design project : series 2 [PDF]

open access: yes, 2017
This book is a compilation of engineering design projects which illustrates a detail explanation on the design process including all tools and methods involved in each design stage.

core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Drivers of Automation and Consequences for Jobs in Engineering Services: An Agent-Based Modelling Approach

open access: yesFrontiers in Robotics and AI, 2021
New technology is of little use if it is not adopted, and surveys show that less than 10% of firms use Artificial Intelligence. This paper studies the uptake of AI-driven automation and its impact on employment, using a dynamic agent-based model (ABM ...
Hildegunn Kyvik Nordås   +2 more
doaj   +1 more source

Engineering design project : series 1 [PDF]

open access: yes, 2017
This book is a compilation of engineering design projects which illustrates a detail explanation on the design process including all tools and methods involved in each design stage.

core  

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