Results 71 to 80 of about 559,594 (297)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Financial frictions and the K/L ratio in UK manufacturing [PDF]
, 2010 We investigate whether technological differences of UK manufacturing industries influence the response of firms’ capital–labour (K/L) ratio to changes in financial indicators under financial frictions.
Spaliara, M.E.
core +2 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Competitiveness of Indian Manufacturing: Finding of the 2001 National Manufacturing Survey [PDF]
In this paper we present findings of the second national survey on the competitiveness of Indian manufacturing. The paper develops hypotheses on the competitiveness of firms in the manufacturing sector and addresses some key questions on the ...
Chandra, Pankaj, Sastry Trilochan
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Thailand Manufacturing Firm Productivity Report [PDF]
, 2020 Thailand is an enduring development success story. Between the late 1960s and mid-1990s, strong and sustained economic growth propelled the country from low-income to upper-middle-income status. To achieve high-income status by 2037, the authorities will need to draw on the experiences of ...
openaire +3 more sources
The Number and Size of Firms: Why So Big a Difference? [PDF]
The number of firms and their size are analysed for the Slovenian manufacturing sector on the basis of the firm-level evidence of the Business Register of Slovenia virtually representing all the firms in activity. A remarkable difference is found between
Ana Xavier, Stefan Bojnec
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
PLoS ONEUnder the global wave of intelligence, intelligent manufacturing has become a crucial means of transforming and upgrading China's manufacturing industry.
Haiyue Liu, Jianwu Ren
doaj +1 more source
Impact of Organisational Innovation on Sustainable Competitive Advantage of Manufacturing Firms in Lagos State, Nigeria [PDF]
Management and Economics ReviewThe increased level of competition in the current business climate required the implementation of processes and systems to guarantee a sustainable organisational competitive advantage for the benefit of stakeholders.
Abdul-Hameed Adeola SULAIMON +4 more
doaj +1 more source