Results 101 to 110 of about 1,340,318 (304)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Discrete Event Simulation Method as a Tool for Improvement of Manufacturing Systems
Computers, 2017 The problem of production flow in manufacturing systems is analyzed. The machines can be operated by workers or by robots, since breakdowns and human factors destabilize the production processes that robots are preferred to perform. The problem is how to
Adrian Kampa +2 more
doaj +1 more source
Towards the development of the supply chain of concentrated solar power [PDF]
, 2016 This work focuses on the investigation into the planning of renewable energy power plants in Brazil using the Concentrated Solar Power (CSP) technology.
Martinez-Conde Moreno, Javier +4 more
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Principles for aerospace manufacturing engineering in integrated new product introduction [PDF]
, 2013 This article investigates the value-adding practices of Manufacturing Engineering for integrated New Product Introduction. A model representing how current practices align to support lean integration in Manufacturing Engineering has been defined.
Beadle, Chris +3 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The influencing mechanism of manufacturing scene change on process domain knowledge reuse [PDF]
, 2013 It is necessary for a enterprise to reuse outside process domain knowledge to develop intelligent manufacturing technology. The key factors influencing knowledge reuse in digital manufacturing scene are manufacturing activities and PPR (Products ...
Ling, Tiezhang +2 more
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Microscale Freeform Integration by Directed Self Assembly [PDF]
, 2007 Most solid freeform fabrication (SFF) manufacturing processes assemble uniform components such as powder particles or polymer chains to produce desired geometries. Their capacity for producing highly functional parts (integrated actuation, sensing, and
Crane, Nathan +3 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Defence Technology, 2017 Aluminium matrix surface composites are gaining alluring role especially in aerospace, defence, and marine industries. Friction stir processing (FSP) is a promising novel solid state technique for surface composites fabrication. In this study, AA6061/SiC
Sandeep Rathee +3 more
doaj +1 more source
Study for identification of Beneficial Uses of Space (BUS) (phase 2). Volume 1: Executive summary [PDF]
A study was conducted to analyze the benefits to the world which can be realized from space manufacturing processes. The study envisaged the use of the space shuttle and manned space stations for the purpose.
core +1 more source