Results 81 to 90 of about 1,340,318 (304)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Low-voltage wearable tactile display with thermo-pneumatic actuation

npj Flexible Electronics
Tactile displays often face challenges like high power consumption, bulky control systems, and limited portability, hindering their application in wearable technologies.
A. Mazzotta, S. Taccola, I. Cesini, M. Sanchez Sifuentes, R. A. Harris, V. Mattoli   +5 more
doaj   +1 more source

Computer Aspects of Solid Freeform Fabrication: Geometry, Process Control, and Design [PDF]

, 1993
Solid Freefonn Fabrication (SFF) is a class of manufacturing technologies aimed at the production of mechanical components without part-specific tooling or process planning. Originally used for creating modelsfor visualization, many industrial users of
Crawford, Richard H.
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Firmware Development Improves System Efficiency [PDF]

, 1993
Most manufacturing processes require physical pointwise positioning of the components or tools from one location to another. Typical mechanical systems utilize either stop-and-go or fixed feed-rate procession to accomplish the task.
Butler, David W., Chern, E. James
core   +1 more source

Micro-manufacturing : research, technology outcomes and development issues [PDF]

, 2010
Besides continuing effort in developing MEMS-based manufacturing techniques, latest effort in Micro-manufacturing is also in Non-MEMS-based manufacturing. Research and technological development (RTD) in this field is encouraged by the increased demand on
A Albers, A Gillner, A Razali, A Yabe, A. Brockett, A. Razali, AJ Sanchez-Salmeron, B Bhattacharyya, B Moser, BH Ryu, C. Harrison, CH Amon, CK Malek, CL Kuo, D Huo, D. Loziak, DT Pham, E Uhlmann, E Uhlmann, GM Robinson, H Aoyama, H Tsukahara, H Zhao, HJ Booth, HN Hansen, I Beltrami, J Cecil, J Fleischer, J Michler, J-M Breguet, J. Zhao, JA MacGeough, JA Palmer, JB Luo, K Ehmann, K Najafi, KP Rajurkar, L Alting, L Philippe, L Zhou, M Asami, M Geiger, M Meier, M Suda, MT Hung, NH Loh, P Bado, PR Hauptmann, R Muckenhirn, RP Martukanitz, S Fatikow, S Fatikow, S Fatikow, S Wakuri, T Gaugel, T Huang, V Kadekar, W Michaeli, W Pfleging, W. Pan, X Luo, X Peng, X Peng, X. Dai, XC Li, Y Li, Y Okazaki, Y Qin, Y. Ma, YB Bang, Yi Qin   +70 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Using Vikor's multi-criteria decision making method to find the best combination of PZT5 in the presence of barium, cobalt and molybdenum additives for use in pressure sensors

Results in Materials
The purpose of this paper is to analyze effect of barium, molybdenum and cobalt additives on the dielectric and piezoelectric properties of Pb(Zr0.52 Ti0.48) O3 ceramics.
Mohammad Hadi Hemati, Hossein Lexian
doaj   +1 more source

FEM-based deformation regression analysis of ECAE strains [PDF]

FME Transactions, 2019
The present article is focused on the regression-based generalization of FEM simulation results, derived through the introduction of QForm 2D FEM software to copper workpieces simulated flow through 2θ angular dies with external R and internal r die ...
Perig Alexander V., Matveyev Ivan A.
doaj