Results 51 to 60 of about 1,574,435 (263)

Simultaneous Measurement of Temperature and Refractive Index Using Michelson Interferometer Based on Waist-Enlarged Fiber Bitaper

open access: yesMicromachines, 2022
An all-fiber temperature and refractive dual-parameter-sensing Michelson interferometer is designed based on the waist-enlarged bitaper. At 5 mm from the fiber end, the waist-enlarged bitaper is manually spliced and the probe is formed.
Na Zhao   +9 more
doaj   +1 more source

Heuristic Solutions for Loading in Flexible Manufacturing Systems [PDF]

open access: yes, 1996
Production planning in flexible manufacturing system deals with the efficient organization of the production resources in order to meet a given production schedule. It is a complex problem and typically leads to several hierarchical subproblems that need
Chen, Wun-Hwa, Srivastava, Bharatendu
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Gate-tunable flexible photodetector with wavelength-selective response based on asymmetric 2D heterostructures

open access: yesMicrosystems & Nanoengineering
Flexible photodetectors with wavelength-selective response are essential for next-generation wearable and bio-integrated optoelectronics. However, conventional devices typically rely on external filters or complex structures, limiting the flexibility ...
Ze Zhang   +7 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

The influencing mechanism of manufacturing scene change on process domain knowledge reuse [PDF]

open access: yes, 2013
It is necessary for a enterprise to reuse outside process domain knowledge to develop intelligent manufacturing technology. The key factors influencing knowledge reuse in digital manufacturing scene are manufacturing activities and PPR (Products ...
Ling, Tiezhang   +2 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

An investigation into the effects of computer integrated manufacturing systems in the productivity of SMEs in Pakistan [PDF]

open access: yes, 2006
The current dynamic and turbulent manufacturing environment has forced companies that compete globally to change their traditional methods of conducting business [Producer to consumer].
Irani, Z, Marri, H B, Shaikh, G
core  

Transforming failure into success through organisational learning: An analysis of a manufacturing information system [PDF]

open access: yes, 2001
This paper describes the idiosyncracies of a case study company, through highlighting issues and problems experienced during their attempts to evaluate, implement and realise the holistic implications of a manufacturing information system. Although the
Irani, Z, Love, PED, Sharif, A M
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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