Results 151 to 160 of about 3,469,998 (360)

A perspective illusion or a view from the clouds? Detail of an Early 16th-Century miniature painting produced in Tabriz (Iran) [PDF]

open access: yes, 2019
A Persian painting (910H/1505) from a manuscript of Nizami’s Khamsa preserved in the Keir Collection portrays the mi'raj of Muḥammad among many angels in a blue sky; the Ka'ba is depicted in the lower foreground while the desert surrounds almost the ...
Fontana, MARIA VITTORIA
core  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

The symphonies of Antonio Brioschi : aspects of sonata form [PDF]

open access: yes, 2009
The article investigates tonal, thematic, and textural aspects of sonata form in the movement structures of twenty-six symphonies from the 1730s and early-1740s by the Italian composer Antonio Brioschi (active ca. 1725–ca. 1750).
Mandel-Yehuda, Sarah
core  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Collecting history : western historical manuscript collection celebrates 40th anniversary [PDF]

open access: yes, 1983
Includes photos from George W. Gardner and from the joint collection of the western historical manuscript collection."At the western historical manuscript collection in Ellis Library, old letters, diaries, journals, and professional and political ...
Caldwell, Diane
core  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

A Preliminary Report on the Sanskrit Manuscript of the Uttaragrantha of the Mūlasarvāstivāda Vinaya

open access: yesReligions
The discovery of the Schøyen–Virginia manuscript of the Uttaragrantha provides significant insights into the Mūlasarvāstivāda Vinaya. This newly identified Sanskrit manuscript offers a fresh perspective on monastic law codes, contributing original ...
Hyebin Lee
doaj   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

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