Results 131 to 140 of about 12,863,015 (313)

Zürich, Braginsky Collection, B331 : Book on circumcision

This small-format manuscript from the 17th century contains hymnal prayers, poems and blessings for the circumcision ceremony. Two sections of the book contain illustrated pages. In addition to the title page, which is decorated with a Renaissance portal,

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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

St. Gallen, Stiftsbibliothek, Cod. Sang. 990 : Composite manuscript of ascetic content with spiritual treatises by the Dominican Monk Wendelin Fabri from Pforzheim

This manuscript was written in the years 1521 and 1522 by the copyists Regina Sattler, Dorothea von Hertenstein and Elisabeth Schaigenwiler in the Dominican Cloister St. Katharina in St.
Sattler, Regina, Fabri, Wendelin, Dorothea, von Hertenstein, Arx, Ildefons von   +3 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Solothurn, Zentralbibliothek, Cod. S 451 : Solothurn Legendary

The Solothurn Legendary is the earliest example of a collection of legends in the German language. This manuscript was written during the second quarter of the 14th century in a Dominican cloister, possibly in Töss (near Winterthur) or in Oetenbach ...
Gotthard, Werner, Seuse, Heinrich
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Fetvava - yi aqhisari: Rukopis u nacionalnoj biblioteci u Beču

Anali Gazi Husrev-Begove Biblioteke, 2005
Topic of this work is one manuscript Collection of the legal opin- ions - whose author is mufti from Budim Ibrahim el-Akhisari. This manuscript, kept in the National Library in Vienna, was catalogued and described by Gustav Flugel.
Nedim Zahirović
doaj  

St. Gallen, Stiftsbibliothek, Cod. Sang. 955 : Composite manuscript of religious content with numerous spiritual theological texts and sermons

This composite manuscript likely is from Rhenish Franconia or from the Upper Rhine area and came into the possession of the Abbey of St. Gall in 1699, probably from the Convent of Poor Clares in Freiburg im Breisgau (like, for example, Cod. Sang.
Johannes, de Basilea, Bertholdus, Ratisbonensis, Tauler, Johannes, Albertus, Magnus   +3 more
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Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Bern, Burgerbibliothek, Cod. 120.I : Composite manuscript: Ado Viennensis: Chronicon; Aurelius Victor (Pseudo-): Epitome de Caesaribus; Abbo Floriacensis: De gestis Romanorum pontificum, lat.

This composite manuscript contains various texts in chronicle form, some of them rare, regarding worldly and ecclesiastical rulers. It is a heavily edited and corrected manuscript from the Benedictine Abbey of Saint-Mesmin de Micy, which contains ...
Bürger, Ulrike, Abbo, Floriacensis, Aurelius Victor, Sextus, Daniel, Pierre, Ado, Viennensis, Bongars, Jacques, Hrabanus, Maurus, Prudentius Clemens, Aurelius, Busaeus, Johannes, Lindt, Johann, Gravisset, Jakob von, Guilelmus, Peraldus   +11 more
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