Results 111 to 120 of about 12,863,015 (313)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Zürich, Braginsky Collection, B49 : Siddur according to the Italian Rite (Nussah Roma)

open access: yes
The Roman rite, generally known as Nussah Roma, is the oldest order of prayer outside the ancient lands of Israel and Babylonia, retaining many old Palestinian traditions. The ornamentation of this manuscript includes many attractive initial word panels,

core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Basel, Universitätsbibliothek, A XI 59 : Ascetic-catechetical composite manuscript

open access: yes
This manuscript, written mostly in German, consists of various parts, all of which probably date from the same time, the end of the 15th century to the beginning of the 16th century.
Freidank   +16 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Zürich, Zentralbibliothek, Ms. C 78 : Manuscript compilation: Alcuin; theological-canonical treatises; sermons from the 14th and 15th centuries

open access: yes
Manuscript compilation from the monastery of St. Gall containing a number of assorted brief texts from the 9th through 15th centuries. Among other items from the 9th century, this manuscript contains the sole exemplar of a document explaining the reasons
Reginbertus, Augiensis   +11 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Visualizing the Linked Manuscript Archive: A Linked Open Data Approach to Analyzing Special Collections Data

open access: yesJournal of Open Humanities Data
Linked Open Data (LOD) has found significant use across several rare book and manuscript (RBM) digital archives in recent decades. LOD methodologies for processing institutional or cross-institutional collections enable practitioners to link objects on ...
Maisie Jones
doaj   +1 more source

Basel, Universitätsbibliothek, M VI 48 : Awrād-i šarīfa

open access: yes
Collection of prayers in the form of litanies (awrād), attributed to a Šayḫ Wafāʾ. The manuscript must have been completed before 1746, because in this year it was consigned to a religious foundation by Bašīr Āġā, a dignitary of the Ottoman court.
Tschudi, Rudolf
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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