Results 121 to 130 of about 12,863,015 (313)

Zürich, Braginsky Collection, B119 : Pentateuch based on the Hillel Codex

The importance of the Braginsky Pentateuch for the textual criticism of the Hebrew Bible is comparable to that of MS L44a of the Library of the Jewish Theological Seminary in New York, copied in Toledo in 1241.

core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Sion/Sitten, Médiathèque Valais, S 97 bis : Composite manuscript with French texts (Pontus and Sidonia, Alain Chartier, Songe de la Pucelle, ...)

This manuscript from the library of Walter Supersaxo (ca. 1402-1482), Bishop of Sion, and of his son Georg (ca. 1450-1529) is a collection of literary French texts with moralizing tendencies; it contains the romance Pontus and Sidonia as well as 15th ...
Supersaxo, Georg, La Tour Landry, Geoffroy de, Supersaxo, Walter, Chartier, Alain   +3 more
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Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

St. Gallen, Stiftsbibliothek, Cod. Sang. 902 : Composite manuscript with Aratus Latinus

School manuscript for the St. Gall monastery school, containing the Greek grammar by Dositheus and a prose version of Aratos of Soloi\u27s didactic poem Phainomena which is illustrated with pen drawings.Online Since: 2005-09 ...
Hrabanus, Maurus, Aratus, Solensis
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Zürich, Braginsky Collection, B115 : Sefer Mitzvot Katan (Small Book of Commandments)

Isaac of Corbeil († 1280) is the author of this halakhic Small Book of Commandments also known as Sefer Mitzvot Katan (abbreviated SeMaK). This abridged version of the 613 positive and negative biblical commandments, and a few additional rabbinic ones ...
Moses, von Zürich
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Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source