Results 101 to 110 of about 4,025,753 (264)

Basel, Universitätsbibliothek, C I 21 : Dominicus de S. Geminiano, Lectura super VI, pars 1

Canonistic manuscript with Dominicus de Sancto Geminiano’s Lectura super librum sextum Decretalium. This volume was written in 1439 by Johannes Berwenstein for Peter Zum Luft, who was teaching at the university of the Council of Basel and who later left ...
Berwenstein, Johannes, Zum Luft, Arnold, Zum Luft, Peter, Dominicus, de Sancto Geminiano   +3 more
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Cologny, Fondation Martin Bodmer, Cod. Bodmer 704 : Bhagavadgītā and subsidiary texts

This manuscript comprises a collection of four different texts. The main text is the Bhagavadgītā ("Song of the Lord"), a part of the Mahābhārata epic, book 6, which consists of 18 chapters, written here in Devanāgarī in a Kashmiri-influenced style (f.

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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Basel, Pharmaziemuseum der Universität Basel, Cod. H87 : Handwritten copy of the pharmacopoeia of Burkart von Hallwyl (1535-1598)

This copy of Burkart von Hallwyl\u27s (1535-1598) pharmacopoeia is a collection of medications and recipes for treating everyday problems. The length of the recipes ranges from a single sentence to detailed texts containing instructions and lists of ...
Hallwyl, Burkhard von
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CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

St. Gallen, Stiftsbibliothek, Cod. Sang. 269 : Isidore of Seville’s Synonyma; Pseudo-Sisbert of Toledo’s corpus; Fulgentius of Ruspe’s De fide; Alcuin’s works.

Copied in St. Gall by a single scribe, this early 10th-century manuscript contains Isidore of Seville’s Synonyma, the so-called corpus of Pseudo-Sisbert of Toledo, Fulgentius of Ruspe’s De fide and a significant collection of Alcuin’s theological ...
Alcuinus, Flaccus, Fulgentius, Claudius Gordianus, Augustinus, Aurelius, Defensor, Locogiacensis, Isidorus, Hispalensis, Sisbertus, Toletanus   +5 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Cologny, Fondation Martin Bodmer, Cod. Bodmer 73 : Gesta romanorum (Ger.)

This manuscript contains the German version of the Gesta Romanorum, a collection of anecdotes and tales originally in Latin that were compiled around the end of the 13th or the beginning of the 14th century.
Bodmer, Martin, Donatus, Aelius, Langer, Eduard, Görres, Joseph von, Hinterberger, Heinrich, Kraus, Hans P.   +5 more
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Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source