Results 81 to 90 of about 4,025,753 (264)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Cologny, Fondation Martin Bodmer, Cod. Bodmer 706 : Kalpasūtra, i.e. "Book of rituals"
This unbound manuscript contains one of the most copied texts of the Śvetāmbara Jaina tradition, the Kalpasūtra, which was very popular all over India from the 14th century on. It is a collection of life stories of the great Tīrthaṅkāras.
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Until it was acquired by the Braginsky Collection, this little book with the Birkat ha-mason from 1741 had not been known to research. Clearly it had originally been meant for a woman, probably as a wedding present.
Jakob Sofer ben Juda Löb, aus Berlin
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
St. Gallen, Stiftsbibliothek, Cod. Sang. 718 : Guilelmus Horborch: Decisiones novae Rotae
This manuscript, probably written in Italy in the second quarter of the 15th century, contains the canonist Wilhelm Horborch’s († 1384) collection of judicial decisions of the Rota Romana.
Pater Pius Kolb +5 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Manuscript compilation from the second half of the 8th century, written and decorated with several extraordinary initials, possibly at a “Swiss center under Burgundian or Irish influence” (Bruckner) or instead “in western Alemannia or in eastern Burgundy”
Faustus, Reiensis +3 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Zürich, Braginsky Collection, B283 : Documents concerning the condemnation and burning of the Talmud
This collection of eleven documents in Italian concerning the condemnation and burning of the Talmud relate to one of the darkest periods in the history of the Hebrew book.
core +1 more source