Results 41 to 50 of about 4,025,753 (264)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Zürich, Braginsky Collection, B243 Vol. 1 : Hebrew Bible

open access: yes
At the end of the last volume (Vol. 4) of this Hebrew Bible with Masoretic comments (textual criticism) is the older colophon, which states that Isaac ben Ishai Sason completed it in 1491 in Ocaña, (Spain).
Botfield, Beriah
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Zürich, Braginsky Collection, B124 : Jacob ben Asher, Tur Orah Hayyim ("Row: Way of Life")

open access: yes
This manuscript by Jacob ben Asher (son of the rabbi and codifier Asher ben Jehiel) contains one of the oldest copies of the Jewish code Arba’ah Turim. The entire work treats all rules of Jewish law concerning prayers and the synagog.
Yaʿaḳov ben Asher
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Zürich, Braginsky Collection, B62 : De Pinto Psalter (Sefer Tehillim)

open access: yes
In 1728 Meir Cohen Belinfante copied this decorated psalter from the 1670 printed edition by the Amsterdam printer of Hebrew and Spanish books, David de Castro Tartas, who was active between 1662 and 1698. The manuscript has a decorated title page, which

core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Basel, Universitätsbibliothek, A VIII 36 : Collection of hagiographic texts

open access: yes
This composite manuscript in German is from the Convent of Dominican nuns of St. Maria Magdalena “an den Steinen” in Basel, which was reformed in 1423; most of the manuscript was probably written there as well.
Biberli, Marquard   +1 more
core   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Basel, Pharmaziemuseum der Universität Basel, Cod. H37 : Johannes Drexell, Collection of medical treatises

open access: yes
This collection is contained in a paper manuscript that originated in Switzerland. Later it received a binding of wooden boards covered in blind-tooled pigskin leather.
Drexel, Johannes
core   +1 more source

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