Results 91 to 100 of about 21,652,091 (264)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Diyarbakır Ziya Gökalp Yazma Eserler Kütüphanesi’nde Bulunan Mantık ve Felsefe ’ye Dair Yazma Eserler

Yakın Doğu Üniversitesi İslam Tetkikleri Merkezi Dergisi, 2016
Bu çalışmada Diyarbakır Ziya Gökalp Yazma Eserler KütüphanesindekiMantık ve Felsefe ile ilgili yazma eserlerin isim ve kayıtnumaraları verilmiştir.
Şerafeddin Adsoy
doaj  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Basel, Universitätsbibliothek, D IV 10 : Composite manuscript (chronicles)

The core of this manuscript from the Carthusian Monastery of Basel is a copy of the Flores temporum, a Latin world chronicle from the 13th century that was widely used in Alemannic areas.
Heinrich Arnoldi, Gerung, Nicolaus, Benevenutus, Imolensis, Louber, Jakob, Iselin, Jakob Christoph   +4 more
core   +1 more source

Revisiting the Sanggau Qur’anic Manuscript: Codicological Findings and Variations in Its Ḍabṭ System

Journal of Islamic History and Manuscript
This study revisits a Qur’anic manuscript from Sanggau preserved in the West Kalimantan Provincial Museum by integrating codicological analysis with an examination of its ḍabṭ system.
Udi Yuliarto, Ihsan Nurmansyah, Sulaiman
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Basel, Universitätsbibliothek, A XI 59 : Ascetic-catechetical composite manuscript

This manuscript, written mostly in German, consists of various parts, all of which probably date from the same time, the end of the 15th century to the beginning of the 16th century.
Freidank, Hippocrates, Caesarius, Heisterbacensis, Bonaventura, Sanctus, Engelhart, von Ebrach, Platon, Johannes, Chrysostomus, Hieronymus, Sophronius Eusebius, Augustinus, Aurelius, Conradus, Marburgensis, Ambrosius, Mediolanensis, Beda, Venerabilis, Seneca, Lucius Annaeus, Isidorus, Hispalensis, Albertus, Magnus, Aristoteles, Bernardus, Claraevallensis   +16 more
core   +1 more source

Parallel Glosses, Shared Glosses, and Gloss Clustering

Journal of Historical Network Research, 2023
Glossing was an important element of medieval Western manuscript culture. Yet, glosses are notoriously difficult to analyze because of their philological triviality, fluid nature, heterogeneity of origin, complex transmission histories, and anonymity ...
Evina Stein
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Zürich, Zentralbibliothek, Ms. C 78 : Manuscript compilation: Alcuin; theological-canonical treatises; sermons from the 14th and 15th centuries

Manuscript compilation from the monastery of St. Gall containing a number of assorted brief texts from the 9th through 15th centuries. Among other items from the 9th century, this manuscript contains the sole exemplar of a document explaining the reasons
Reginbertus, Augiensis, Walahfridus, Strabo, Alcuinus, Flaccus, Serenus, Quintus, Laurentius, de Londorio, Theodulfus, Aurelianensis, Augustinus, Aurelius, Columbanus, Sanctus, Beda, Venerabilis, Venantius, Fortunatus, Angilbertus, Centulensis, Isidorus, Hispalensis   +11 more
core   +1 more source