Results 101 to 110 of about 21,652,091 (264)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

St. Gallen, Stiftsbibliothek, Cod. Sang. 902 : Composite manuscript with Aratus Latinus

open access: yes
School manuscript for the St. Gall monastery school, containing the Greek grammar by Dositheus and a prose version of Aratos of Soloi\u27s didactic poem Phainomena which is illustrated with pen drawings.Online Since: 2005-09 ...
Hrabanus, Maurus, Aratus, Solensis
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Exploring the needs of Malay manuscript studies community for an e-learning platform [PDF]

open access: yes, 2011
Philology studies are often associated with traditional methods of teaching and learning. This study explores the possibility of e-learning adoption amongst Malay manuscripts learning community.
Zainab, A.N.   +6 more
core   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

St. Gallen, Stiftsbibliothek, Cod. Sang. 990 : Composite manuscript of ascetic content with spiritual treatises by the Dominican Monk Wendelin Fabri from Pforzheim

open access: yes
This manuscript was written in the years 1521 and 1522 by the copyists Regina Sattler, Dorothea von Hertenstein and Elisabeth Schaigenwiler in the Dominican Cloister St. Katharina in St.
Sattler, Regina   +3 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

St. Gallen, Stiftsbibliothek, Cod. Sang. 955 : Composite manuscript of religious content with numerous spiritual theological texts and sermons

open access: yes
This composite manuscript likely is from Rhenish Franconia or from the Upper Rhine area and came into the possession of the Abbey of St. Gall in 1699, probably from the Convent of Poor Clares in Freiburg im Breisgau (like, for example, Cod. Sang.
Johannes, de Basilea   +3 more
core   +1 more source

Phytolith assemblages from palm leaves and palm-leaf manuscripts: what is the difference and what it could mean?

open access: yesFrontiers in Plant Science
We studied freshly collected, dried and herbarized leaf fragments of two palms, namely Borassus flabellifer L. and Corypha umbraculifera L., most commonly used for palm-leaf manuscript (PLM) production in South (S) and Southeast Asia (SE) in order to ...
Anastasia Poliakova   +11 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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