Results 101 to 110 of about 6,967,624 (274)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Visualizing the Fight Book Tradition
The Thun-Hohenstein album, long-known as the Thun’sche Skizzenbuch, is a bound collection of 112 drawings that visualize armoured figures at rest and in combat, as well as empty armours arrayed in pieces.
Chassica Kirchhoff
doaj
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Programme Of Studies In Oriental Manuscripts
Project presentation: Programme of Studies in Oriental ...
openaire +2 more sources
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Bu çalışmada Diyarbakır Ziya Gökalp Yazma Eserler KütüphanesindekiMantık ve Felsefe ile ilgili yazma eserlerin isim ve kayıtnumaraları verilmiştir.
Şerafeddin Adsoy
doaj
Parallel Glosses, Shared Glosses, and Gloss Clustering
Glossing was an important element of medieval Western manuscript culture. Yet, glosses are notoriously difficult to analyze because of their philological triviality, fluid nature, heterogeneity of origin, complex transmission histories, and anonymity ...
Evina Stein
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Ethiopian manuscripts and Ethiopian manuscript studies: a brief overview and evaluation
Nosnitsin Denis. Ethiopian Manuscripts and Ethiopian Manuscript Studies. A brief Overview and Evaluation. In: Gazette du livre médiéval, n°58. 2012, fasc. 1. pp. 1-16.
Nosnitsin, Denis
openaire +3 more sources

