Results 51 to 60 of about 354,448 (304)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The Manuscript Tradition of Xenophon’s Apologia Socratis

open access: yesGreek, Roman, and Byzantine Studies, 2005
[site under construction]
Edward A. Schmoll
doaj  

A Psalter from Tübingen: Although Inconspicuous the Text, Neverthless a Treasure for Manuscriptology

open access: yesAethiopica, 2011
The University Library of Tübingen, Germany, has acquired a manuscript with the text of a Mäzmurä Dawit. The manuscript is dated. At first glance it seems to be the standard Psalter.
Veronika Six
doaj   +1 more source

Obraz i tekst w służbie Absolutu. Manuskrypt średniowieczny a idea dzieła totalnego [PDF]

open access: yes, 2012
The article takes up the problem of the medieval manuscript as an example of a total work of art.  Miniature  painting  is  an  example  of  diffusional  transmittance  of  the  various  semiotic orders, which define each other and lead to the creation ...
Prałat, Emilian
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Fiddle tunes in eighteenth-century Wales [PDF]

open access: yes, 2006
Publisher ...
Meurig, Cass
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

ANSELM OF LUCCA’S «COLLECTION OF CANONS» AND ITS MANUSCRIPT TRADITION [PDF]

open access: yesВестник Православного Свято-Тихоновского гуманитарного университета: Серия I. Богословие, философия, 2011
This article deals with the renewal of Roman law and its reception and interpretation by canonists of the Roman Catholic Church. This process achieved its fi nal form in Anselm of Lucca’s (1036–1086) Collection of Canons and constituted the legal corpus ...
A. MITROPHANOV
doaj  

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