Results 81 to 90 of about 114,970 (245)
The Poor and the Patient: Protestant Geneva in the Early Modern Period 1 [PDF]
ecent research has demonstrated the usefulness of considering both the history of lay and professional practices from the patient’s point of view. Issues explored include the interactions between the ill and contemporary healers 2, between medical ...
Philip Rieder
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Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The cooperation agreement beetwen the university of l'Aquila, Italy and the Marat Ospanov west-Kazakistan stare medical university, the republic of Kazakistan: a successful story fron academy to bench [PDF]
During the spring-summer of 2014, the first exchange program foreseen the research mobility from Kazakhstan to Italy. An academic staff member and a PhD student of the Marat Ospanov WestKazakhstan State Medical University spent three months of research ...
Rakhmanov, S. +11 more
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OBML - Ontologies in Biomedicine and Life Sciences. [PDF]
The OBML 2010 workshop, held at the University of Mannheim on September 9-10, 2010, is the 2nd in a series of meetings organized by the Working Group "Ontologies in Biomedicine and Life Sciences" of the German Society of Computer Science (GI) and the ...
Schulz, Stefan +14 more
core +2 more sources
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Dear reader, We have entered the final year of the first quarter of the 21st century, which will be eternally marked by the catastrophic challenges linked to numerous global military conflicts and the COVID-19 pandemic.
Oksana Zayachkivska +6 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Clinical molecular genetics in the UK c.1975-c.2000 [PDF]
seminar transcriptChaired by Professor Martin Bobrow and introduced by Professor Bob Williamson, this Witness Seminar included geneticists from a broad range of research and clinical specialities.
Jones, EM, Tansey, EM
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The evolution of medicine trought Renaissance [PDF]
This review of historical medical literature aims to portray the relationship between the philosophical identity of ancient Greece and Christianity and medical progress.
Ballini A. +6 more
core +1 more source

