Results 71 to 80 of about 166,756 (292)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Bohemian manuscripts in the Beinecke Rare Book & Manuscript Library.
, 2022 The Beinecke Rare Book & Manuscript Library has a collection of rare manuscripts, some of which have a direct connection to Bohemian environment, either because they originated here or were part of medieval institutions and their libraries.
Hadaš, Jiří
core
Revista Latinoamericana de Bioética, 2015 Ethics in research became a central theme regarding globalization of the scientific development, particularly when related to the socioeconomic conditions of the countries involved as partners in research protocols, production of inputs and of knowledge.
Flavia Squinca +2 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Stephan, Geraldine, 1912-2003 (SC 2087)
, 2009 Finding aid and scan (Click on Additional Files below) for Manuscripts Small Collection 2087. Outline for a paper: Social and Economic Problems of Bowling Green written by Geraldine Stephan.
Folklife Archives, Manuscripts &
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What happens to medical articles submitted in Spanish that are not accepted for publication?
Neurología (English Edition), 2013 Introduction: The fate of manuscripts submitted and subsequently rejected by Spanish-language journals is unknown. The present study was designed to determine whether or not articles submitted to NEUROLOGÍA are published following rejection, and if so ...
J.A. Matías-Guiu +4 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Brown, Michael R. - Collector (SC 3088)
, 2017 Finding Aid only for Manuscripts Small Collection 3088. Correspondence of Janice Holt Giles related to the “White Caps,” the Brethren in Christ church, and collected by Michael R. Brown for a scholarly article he produced on the topic.
Folklife Archives, Manuscripts &
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source