Results 131 to 140 of about 7,752,729 (310)

Towards optimal scheduling policy for heterogeneous memory architecture in many-core system

, 2018
With the advent of Intels second-generation many-core processor (Knights Landing: KNL), high-bandwidth memory (HBM) with potentially five times more bandwidth than existing dynamic random-access memory has become available as a valuable computing ...
김직수, 남덕윤, 노승우, 박근철   +3 more
core  

Scalable Dynamic Task Scheduling on Adaptive Many-Core

, 2018
Workloads from autonomous systems project an unprecedented processing demand onto their underlying embedded processors. Workload comprises of an ever-changing mix of multitudes of sequential and parallel tasks.
Anuj Pathania, Henkel, Jorg, Mitra, T., Pathania, Anuj, Jorg Henkel, Venkataramani, Vanchinathan, Muhammad Shafique, Shafique, Muhammad, Mitra, Tulika, Venkataramani, V., Shafique, M., Tulika Mitra, Pathania, A., Vanchinathan Venkataramani   +13 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

An Evolutionary Toolchain for Morphological Filter Mapping on Many-Core Architectures

IEEE Access
Many-core systems are systolic architectures consisting of an arbitrarily large number of processing nodes connected by a point-to-point communication network.
Emerson C. Pedrino, Denis P. Lima, Igor F. Gallon, Valentin O. Roda, Naijia Liu, Gianluca Tempesti   +5 more
doaj   +1 more source

Operating System and Scheduling for Future Multi-core and Many-Core Platforms

, 2017
In this chapter, an overview is made on the limitations of the nowadays OS support for multicore systems, when applied to the future and emerging many-core, massively parallel and distributed platforms.
CUCINOTTA, TOMMASO, LIPARI, Giuseppe, Lutz Schubert, Tommaso Cucinotta, Giuseppe Lipari   +4 more
core   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Core Many-to-one Matchings by Fixed-point Methods [PDF]

We characterize the core many-to-one matchings as fixed points of a map. Our characterization gives an algorithm for finding core allocations; the algorithm is efficient and simple to implement.
Federico Echenique, Jorge Oviedo
core