Results 111 to 120 of about 7,752,729 (310)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

An FMM Based on Dual Tree Traversal for Many-Core Architectures

Journal of Algorithms & Computational Technology, 2013
The present work attempts to integrate the independent efforts in the fast N-body community to create the fastest N -body library for many-core and heterogenous architectures.
R. Yokota
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Efficient computation of motif discovery on Intel Many Integrated Core (MIC) Architecture

BMC Bioinformatics, 2018
Background Novel sequence motifs detection is becoming increasingly essential in computational biology. However, the high computational cost greatly constrains the efficiency of most motif discovery algorithms.
Shaoliang Peng, Minxia Cheng, Kaiwen Huang, YingBo Cui, Zhiqiang Zhang, Runxin Guo, Xiaoyu Zhang, Shunyun Yang, Xiangke Liao, Yutong Lu, Quan Zou, Benyun Shi   +11 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Accelerating ray tracing engine of BLENDER on the new Sunway architecture

Engineering Reports
With the increasing popularity of high‐resolution displays, there is a growing demand for more realistic rendered images. Ray tracing has become the most effective algorithm for image rendering, but its complexity and large amount of computing data ...
Zhaoqi Sun, Zhen Wang, Mengyuan Hua, Puyu Xiong, Wubing Wan, Ping Gao, Wenlai Zhao, Zhenchun Huang, Lin Han   +8 more
doaj   +1 more source

A Parallel Genetic Algorithm With Dispersion Correction for HW/SW Partitioning on Multi-Core CPU and Many-Core GPU

IEEE Access, 2018
In hardware/software (HW/SW) co-design, hardware/software partitioning is an essential step in that it determines which components to be implemented in hardware and which ones in software. Most of HW/SW partitioning problems are NP hard.
Neng Hou, Fazhi He, Yi Zhou, Yilin Chen, Xiaohu Yan   +4 more
doaj   +1 more source

Element 3 Chairs and Course List Core General Education Assessment, 2017-2018

, 2018
The Chairs and Course List for Element 3 - Interdisciplinary Global Studies as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core  

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source