Results 91 to 100 of about 7,752,729 (310)
Element 3 Instructions for Core Course Assessment Plan Core General Education Assessment, 2017-2018
, 2018 The Core Course Assessment Plan for Element 3 - Interdisciplinary Global Studies as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Element 2 Chairs and Course List Core General Education Assessment, 2019-2020
, 2020 The Chairs and Course List for Element 2 - Mathematics as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core
, 2018 Many-Core Levels (MCL) is a framework that allows one to write computational kernels for different kinds of many-core ...
Hijma, Pieter +3 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Response Time Analysis With Cause-Effect Chain Considering DAG Structure and High-Load Tasks
IEEE AccessRecent developments in autonomous driving systems highlight the significance of response time analysis. In autonomous driving systems, the complexities of response time analysis stem from different periods of tasks, tasks with high computational demands (
Tomoya Kobayashi +2 more
doaj +1 more source
Highly concurrent stream synchronization in many-core embedded systems
, 2016 Embedded many-core architectures are expected to serve as significant components in the infrastructure of upcoming technologies like networks for the Internet of Things (IoT), facing real-time and stream processing challenges. In this work we explore the
Nikolakopoulos, Ioannis +11 more
core +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source