Results 91 to 100 of about 5,251,663 (307)
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Credible Group Stability in Many-to-Many Matching Problems [PDF]
It is known that in two-sided many-to-many matching problems, pairwise stable matchings may not be immune to group deviations, unlike in many- to-one matching problems (Blair 1988). In this paper, we show that pairwise stability is equivalent to credible
Hideo Konishi, M. Utku Ünver
core
Fragmentation in the Serpens/Aquila Star-forming Region
The Astrophysical JournalWe present a population study of Atacama Large Millimeter/submillimeter Array (ALMA) Cycle 6 observations of the 100 most gravitationally unstable dense cores in Aquila using a simple mass versus size analysis.
Samuel D. Fielder +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Cores Symposium on Radiation in the Environment : Scientific Achievements and Challenges for the Society [PDF]
, 2018 The Finnish Consortium for Radiation Safety Research (Cores) organized a symposium “Radiation in the environment – scientific achievements and challenges for the society” in Helsinki on April 16–17, 2018.
Lusa, Merja +2 more
core
Virus-producing cells determine the host protein profiles of HIV-1 virion cores
Retrovirology, 2012 Background Upon HIV entry into target cells, viral cores are released and rearranged into reverse transcription complexes (RTCs), which support reverse transcription and also protect and transport viral cDNA to the site of integration.
Santos Steven +4 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Fluid-film lubrication computing with many-core processors and graphics processing units
Advances in Mechanical Engineering, 2018 The advancement of modern processors with many-core and large-cache may have little computational advantages if only serial computing is employed. In this study, several parallel computing approaches, using devices with multiple or many processor cores ...
Nenzi Wang, Hsin-Yi Chen, Yu-Wen Chen
doaj +1 more source
Microgrid - The microthreaded many-core architecture
CoRR, 2013 30 pages, 16 ...
openaire +2 more sources
Many-Task Computing on Many-Core Architectures
Scalable Computing: Practice and Experience, 2016 Many-Task Computing (MTC) is a common scenario for multiple parallel systems, such as cluster, grids, cloud and supercomputers, but it is not so popular in shared memory parallel processors. In this sense and given the spectacular growth in performance and in number of cores integrated in many-core architectures, the study of MTC on such architectures ...
Pedro Valero-Lara +5 more
openaire +3 more sources