Results 81 to 90 of about 5,251,663 (307)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 2016 Educação Infantil::Natureza e sociedadeGuia de experimento que permite demonstrar que através de todas as cores pode-se obter a cor branca. Para realizar essa experiência é necessário uma cartela (redonda) com várias cores e um CD para colocar o papel ...
Nunes, Vaz
core +1 more source
Analysis of Memory System of Tiled Many-Core Processors
IEEE Access, 2019 Tiled many-core processors are designed to integrate simple cores onto a single chip to take advantage of software-level parallelism, and these cores are interconnected via mesh-based networks to mitigate overheads such as limited throughput derived from
Ye Liu, Shinpei Kato, Masato Edahiro
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
, 2015 The Digital Grain Size Project: Automated Estimates of Grain Size from Images of Sediment.
Daniel Buscombe
core +1 more source
, 2011 Guia de experimento que permite demonstrar que através de todas as cores pode-se obter a cor branca. Para realizar essa experiência é necessário uma cartela (redonda) com várias cores e um CD para colocar o papel com as cores em cimaEducação Infantil ...
Nunes, Vaz
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Hardware/Software Helper Thread Prefetching On Heterogeneous Many Cores
, 2014 International audience—Heterogeneous Many Cores (HMC) architectures that mix many simple/small cores with a few complex/large cores are emerging as a design alternative that can provide both fast sequential performance for single threaded workloads and ...
Seznec, André +5 more
core +1 more source
Performance modeling and analysis of parallel Gaussian elimination on multi-core computers
Journal of King Saud University: Computer and Information Sciences, 2014 Gaussian elimination is used in many applications and in particular in the solution of systems of linear equations. This paper presents mathematical performance models and analysis of four parallel Gaussian Elimination methods (precisely the Original ...
Fadi N. Sibai
doaj +1 more source