Results 61 to 70 of about 172,768 (247)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Map Matching Based on Seq2Seq with Topology Information
Applied Sciences, 2023 Most existing road network matching algorithms are designed based on previous rules and do not fully utilize the potential of big data and historical tracks. To solve this problem, we introduce a new road network matching algorithm based on deep learning
Yulong Bai +5 more
doaj +1 more source
An Approach to Vehicle Trajectory Prediction Using Automatically Generated Traffic Maps
, 2018 Trajectory and intention prediction of traffic participants is an important task in automated driving and crucial for safe interaction with the environment.
Hu, Haohao +3 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Dense spatio‐temporal stereo matching for intelligent driving systems
IET Image Processing, 2021 This paper addresses the problem of matching stereo images acquired by a stereo system mounted aboard an intelligent vehicle. The main idea behind the new method consists in involving temporal matching between a current stereo pair and its preceding one ...
Zakaria Kerkaou +3 more
doaj +1 more source
Multi-hypothesis Map-Matching using Particle Filtering [PDF]
, 2009 8 pagesInternational audienceThis paper describes a new Map-Matching method relying on the use of Particle Filtering. Since this method implements a multi-hypothesis road-tracking strategy, it is able to handle ambiguous situations arising at junctions ...
Bonnifait, Philippe +3 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Automated Top View Registration of Broadcast Football Videos
, 2017 In this paper, we propose a novel method to register football broadcast video frames on the static top view model of the playing surface. The proposed method is fully automatic in contrast to the current state of the art which requires manual ...
Bhat, Bharath +3 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source