De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties
NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang+25 more
wiley +1 more source
Proteomic surveys of the mouse heart unveil cardiovascular responses to nitric oxide/cGMP signaling deficiencies. [PDF]
Mohanty I+12 more
europepmc +1 more source
The Arabidopsis MAP kinase kinase MKK1 participates in defence responses to the bacterial elicitor flagellin [PDF]
Bardóczy, V.+10 more
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The formation of stable clusters of gold nanoparticles with oligonucleotides at different solution conditions is explored. DNA base homogeneity and strand directionality influence the binding with gold nanoparticles leading to interesting clustering behavior that can be relevant for SERS applications.
Shaila Thakur+3 more
wiley +1 more source
A Structural Insight Into Two Important ErbB Receptors (EGFR and HER2) and Their Relevance to Non-Small Cell Lung Cancer. [PDF]
Topalan E+8 more
europepmc +1 more source
Nucleus Accumbens Proteome Disbalance in an Adolescent Mouse Model of Schizophrenia and Nicotine Misuse Comorbidity. [PDF]
Souza TP+7 more
europepmc +1 more source
Cannabidiol potentiates p53-driven autophagic cell death in non-small cell lung cancer following DNA damage: a novel synergistic approach beyond canonical pathways. [PDF]
Jeon Y+8 more
europepmc +1 more source
Evaluation of Prognostic Implication of Serum Mixed Lineage Kinase Domain-Like Protein in Acute Primary Supratentorial Intracerebral Hemorrhage: A Multicenter Prospective Cohort Study. [PDF]
Ma Y+9 more
europepmc +1 more source
TIMP1 secretion induced by <i>Toxoplasma</i> effector GRA24 via p38 MAPK signaling promotes non-disruptive parasite translocation across polarized brain endothelial monolayers. [PDF]
Afanaseva E, Barragan A.
europepmc +1 more source