Results 311 to 320 of about 1,035,719 (353)

Platelet factor 4 (PF-4)–induced neutrophil adhesion is controlled by src-kinases, whereas PF-4–mediated exocytosis requires the additional activation of p38 MAP kinase and phosphatidylinositol 3-kinase [PDF]

Blood, 2004
AbstractAmong the various chemokines that are functionally active on neutrophils, platelet factor 4 (PF-4; CXCL4) appears to have a specialized role. Lacking typical chemokine activities, PF-4 stimulates neutrophils to undergo firm adhesion to endothelial cells and, in the presence of an appropriate costimulus like tumor necrosis factor (TNF), PF-4 ...
Kasper, Brigitte, Brandt, Ernst, Bulfone-Paus, Silvia, Petersen, Frank   +3 more
openaire   +5 more sources

MAP kinase is involved in IL-4 dependent cytokine expression by human intestinal mast cells

Journal of Allergy and Clinical Immunology, 2002
M Wilke, M.P. Manns, Axel Lorentz, Stephan C. Bischoff   +3 more
openaire   +3 more sources

Reciprocal relationship between expression of MAP Kinase 4 and MAP Kinase 6 during pathogenesis ofAlternariaBlight inArabidopsis thaliana [PDF]

Biotech Today : An International Journal of Biological Sciences, 2016
Arabidopsis thaliana was shown to be an alternate host plant for the disease, Alternaria blight of Brassica and used as a model plant to delineate the relationship between MAP Kinase 4 (MAPK4) and MAP Kinase 6 (MAPK6) during pathogenesis of Alternaria blight.
Gohar Taj, Anil Kumar, Dinesh Pandey, Rakesh Mondal   +3 more
openaire   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Design and Synthesis of 4-Azaindoles as Inhibitors of p38 MAP Kinase

Journal of Medicinal Chemistry, 2003
Inhibition of the biosynthesis of proinflammatory cytokines such as tumor necrosis factor and interleukin-1 via p38 has been an approach toward the development of a disease modifying agent for the treatment of chronic inflammation and autoimmune diseases.
Eva Papp, Rick Roberts, Kyung Song, Alejandra Trejo, Pete William Dunten, Michelle F. Browner, Phyllis E. Whiteley, JoAnn LaFargue, Sushmita Chanda, Paul Weller, Daniel D. Comer, Jose Freire-Moar, David Michael Goldstein, Florentino Sanpablo, Jennifer L. Miller, Mary Welch, Soan Cheng, Saunders John, Stephen D. Warren, Julie Lim, Armando G. Villaseñor, Deborah Carol Reuter, Brett Lovejoy, Lu Zeng, Humberto Bartolome Arzeno, Stacie A. Dalrymple, Mcintosh Joel   +26 more
openaire   +3 more sources

Divergent regulation by p44/p42 MAP kinase and p38 MAP kinase of bone morphogenetic protein‐4‐stimulated osteocalcin synthesis in osteoblasts

Journal of Cellular Biochemistry, 2002
AbstractIn the present study, we investigated whether the mitogen‐activated protein (MAP) kinase superfamily is involved in the bone morphogenetic protein (BMP)‐4‐stimulated synthesis of osteocalcin in osteoblast‐like MC3T3‐E1 cells. BMP‐4 dose‐dependently stimulated osteocalcin synthesis.
Daijiro Hatakeyama, Toshihiko Uematsu, Osamu Kozawa   +2 more
openaire   +3 more sources

p38 MAP kinase regulates BMP-4-stimulated VEGF synthesis via p70 S6 kinase in osteoblasts

American Journal of Physiology-Endocrinology and Metabolism, 2003
We previously reported that p70 S6 kinase takes part in bone morphogenetic protein-4 (BMP-4)-stimulated vascular endothelial growth factor (VEGF) synthesis in osteoblast-like MC3T3-E1 cells. Recently, we showed that BMP-4-induced osteocalcin synthesis is regulated by p44/p42 MAP kinase and p38 MAP kinase in these cells.
Shigeru Akamatsu, Yutaka Oiso, Haruhiko Tokuda, Osamu Kozawa, Toshiyuki Shibata, Daijiro Hatakeyama   +5 more
openaire   +3 more sources

Rho-kinase limits BMP-4-stimulated osteocalcin synthesis in osteoblasts: Regulation of the p38 MAP kinase pathway

Life Sciences, 2014
We previously reported that bone morphogenetic protein-4 (BMP-4) stimulates the synthesis of osteocalcin via p38 mitogen-activated protein (MAP) kinase in osteoblast-like MC3T3-E1 cells, whereas p44/p42 MAP kinase plays as a negative regulator in the synthesis.
Akira Kondo, Rie Matsushima-Nishiwaki, Jun Mizutani, Takanobu Otsuka, Haruhiko Tokuda, Naohiro Yamamoto, Gen Kuroyanagi, Osamu Kozawa   +7 more
openaire   +2 more sources

Structural and signaling requirements of the human melanocortin 4 receptor for MAP kinase activation

Regulatory Peptides, 2007
In addition to its well known stimulation of cAMP production, the human melanocortin type 4 (hMC4) receptor recently has been shown to mediate p44/42 MAPK activation. This finding opens new questions about the structural and signaling mechanisms that connect the receptor to this alternate cell signaling pathway.
Steven J. Fluharty, Caroline S. Patten, Derek Daniels, Aae Suzuki, Daniel K. Yee   +4 more
openaire   +3 more sources