Results 161 to 170 of about 1,192,359 (196)

The "DDVF" motif used by viral and bacterial proteins to hijack RSK kinases mimics a short linear motif (SLiM) found in proteins related to the RAS-ERK MAP kinase pathway. [PDF]

PLoS Pathog
Veinstein M, Stroobant V, Wavreil F, Michiels T, Sorgeloos F.   +4 more
europepmc   +1 more source

Endoplasmic reticulum stress disrupts signaling via altered processing of transmembrane receptors. [PDF]

Cell Commun Signal
Bosakova M, Abraham SP, Wachtell D, Zieba JT, Kot A, Nita A, Czyrek AA, Koudelka A, Ursachi VC, Feketova Z, Rico-Llanos G, Svozilova K, Kocerova P, Fafilek B, Gregor T, Kotaskova J, Duran I, Vanhara P, Doubek M, Mayer J, Soucek K, Krakow D, Krejci P.   +22 more
europepmc   +1 more source

Research Hotspots and Frontier Trends of Autophagy in Diabetic Cardiomyopathy From 2014 to 2024: A Bibliometric Analysis. [PDF]

J Multidiscip Healthc
Yan M, Zhang S, Liang P, Huang H, Li G, A R, Wu H.   +6 more
europepmc   +1 more source

Network pharmacology and in silico analysis reveal Kochiae Fructus as a potential therapeutic against atopic dermatitis through immunomodulatory pathway interactions. [PDF]

PLoS One
Khan SA.
europepmc   +1 more source

Increased SOX10, p16, and Cyclin D1 Immunoreactivity Differentiates MAP Kinase-activated Low-grade Gliomas From Piloid Gliosis. [PDF]

Am J Surg Pathol
Tang V, Zhang KY, Mirchia K, Lu R, Guney E, Terry M, Ligon AH, Ligon KL, Eberhart CG, Perry A, Lucas CG.   +10 more
europepmc   +1 more source

Notch, β-catenin and MAPK signaling segregate endoderm and mesoderm germ layer identities in the diploblast Nematostella vectensis

Haillot E, Lebedeva T, Steger J, Genikhovich G, Montenegro JD, Cole AG, Technau U.   +6 more
europepmc   +1 more source

Studies on MAP Kinase Signaling in the Immune System

, 2010
The primary function of the immune system is to protect the organism from invading pathogens. In response to pathogen invasion, multiple signaling pathways are activated in immune cells, leading to diverse immune defense mechanisms. Chief among these pathways is the activation of MAPKs, which are crucial for transcriptional and nontranscriptional ...
Richard A. Flavell, Hongbo Chi
openaire   +5 more sources

The mitogen-activated protein kinases system (MAP kinase cascade): its role in skin signal transduction. A review

Journal of Dermatological Science, 1996
Mitogen-activated protein (MAP) kinases are proline-directed kinases which are downstream components of a pathway involving p21ras and the serine/threonine kinase Raf-1. They represent an important link between the signal transduction processes at the level of the plasma membrane and the final nuclear events.
Marcus Wieprecht, Constantin E. Orfanos, Christoph C. Geilen   +2 more
openaire   +4 more sources

Tumor Evasion of the Immune System: Inhibiting p38 MAP Kinase Signaling Restores the Function of Dendritic Cells.

Blood, 2005
Abstract Dendritic cells (DCs) from cancer patients are functionally defective, however, molecular mechanisms underlying are still poorly understood. In this study, we used the murine 5TGM1 myeloma model to examine the effect and mechanism of tumor-derived factors on the differentiation and function of DCs. Myeloma cells (5TGM1) or tumor
Siqing Wang, Jianfei Wang, Qing Yi, Jing Yang, Michele Wezeman, Larry W. Kwak   +5 more
openaire   +3 more sources