Results 211 to 220 of about 381,210 (291)

Mechanism of quercetin in the treatment of endometriosis based on network pharmacology and transcriptome sequencing. [PDF]

Sci Rep
Huang J, Ding J, Wang J, Zhang Y, Sun B, Hu G, Chen J.   +6 more
europepmc   +1 more source

Data Sheet 1_Tricin selectively combats KRAS-mutant non-small cell lung cancer by inhibiting the PDGF-BB-induced SRC/MAPK/AP-1/PD-L1 signaling pathway and potentiating the antitumor effect of an anti-PD-1 antibody.pdf

Jia-Xin Li (1489726), Shi-Yu Tan (21556103), Li-Qi Li (13861262), Yu-Hong Zheng (21556106), Lin Zhao (92451), Hui-Rong Zhu (15068265), Hai-Lang He (1792132), Yan-Yu Zhang (11870240), Run-Ze Li (8263305), Tian-Yu Bao (21556109), Yi-Zhong Zhang (21556142), Xiao-Man Yang (21556145), Hao Zhang (15339), Hui-Hui Chen (10779241), Bo-Wen Wu (6415742), Xin Lin (149944), Xiao-Sheng Lin (21104909), Yin Cheng Lin (21556148), Xin-Bing Sui (4869961), Ying Xie (50016), Xian-Mei Zhou (1792144), Pei-Yu Yan (10779253)   +21 more
openalex   +1 more source

HSV‑TK/GCV can induce cytotoxicity of retinoblastoma cells through autophagy inhibition by activating MAPK/ERK

, 2018
Quanyong Yi, Zhi‐Sha Bai, Bin Cai, Nan Chen, Li‐Shuang Chen, Tao Yuan, Jinghai Mao   +6 more
openalex   +2 more sources

Ascites circRNA ASCOR Drives Platinum Resistance of High‐Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation

Advanced Science, EarlyView.
High‐grade serous ovarian carcinoma (HGSOC) is plagued by platinum resistance, with malignant ascites closely linked to poor outcomes. Here, we identify ASCOR, a circRNA enriched in ascites small extracellular vesicles (sEVs) from platinum‐resistant HGSOC patients, as a predictor of poor survival. ASCOR enhances platinum resistance in vitro and in vivo
Hanyuan Liu, Chenchen Zhu, Xuelin Yao, Yi Liu, Jing Zhu, Yuebo Li, Hanjie Xu, Cheng Peng, Ge Shan, Liang Chen, Ying Zhou   +10 more
wiley   +1 more source

Data Sheet 1_Transcriptome analysis reveals early activation of MAPK pathways involved in the resistance of Setaria italica against Pyricularia setariae.csv

Shang Feng (17748984), Jia Liu (41593), Xinpeng Han (6269522), Tingting Liu (267387), Saiya Wang (22696346), Shaoshuai Xin (22696349), Zhimin Hao (3843529), Zhiyong Li (47765)   +7 more
openalex   +1 more source

Novel plasminogen activator inhibitor-1-derived peptide protects against impairment of cerebrovasodilation after photothrombosis through inhibition of JNK MAPK

, 2010
William M. Armstead, John Riley, J. Willis Kiessling, Douglas B. Cines, Abd Al‐Roof Higazi   +4 more
openalex   +2 more sources

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

Advanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang, Tingting Qu, Qibing Sun, Ran Li, Junfei Dong, Yuming Du, Ziyin Xuan, Lei Wang, Hanli Li, Jianyun Sun, Fangliang Chen, Jinshuai Liu, Zifan Yang, Jianxiang Lei, Qian Yang, Bin Wang, Zhiming Zhou, Yu Wang   +17 more
wiley   +1 more source

Integrated proteomic and phosphoproteomic analysis reveals the MAPK cascade as a key regulator of ethylene-induced latex production in Hevea brasiliensis. [PDF]

Stress Biol
Yang L, Yuan B, Fang F, He M, Li W, Hui S, Du X, He L, Lui H, Sang T, Wang X.   +10 more
europepmc   +1 more source

Video 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4

Lina Ouologuem (22489549), Anna Kübler (22489552), Sarah Ouologuem (18993381), Amar Hadzic (22489555), Jan B. Stöckl (22489558), Anna Chiara Siciliano (19503451), Stefania Forciniti (14304053), Salvatore Nigro (515706), Helena Iuele (19503445), Valentina Onesto (7534433), Anny Nguyen (22489567), Dana Matzek (13958444), Carla Abrahamian (14798368), Christian Grimm (84987), Bastian Popper (3152211), Giuseppe Gigli (1283514), Loretta L. del Mercato (12401327), Olivia M. Merkel (1315164), Thomas Fröhlich (4542784), Sebastian Theurich (10747727), Karin Bartel (6285329)   +20 more
openalex   +1 more source

Baicalin Promotes Apoptosis of Human Medullary Breast Cancer via the ERK/p38 MAPK Pathway [PDF]

Xindong Li, Qianqian Tang, Wenwei Li, Dongzai Zhan, Xiangyang Fang, Sheng‐Chao Huang, Xiaorong Shui, Jianwen Li   +7 more
openalex   +1 more source