Results 211 to 220 of about 514,036 (239)

Investigating the Mechanism of the Fuzheng Huayu Formula in Treating Cirrhosis through Network Pharmacology, Molecular Docking, and Experimental Verification. [PDF]

ACS Omega
Yu R, Shi R, Chen J, Zheng X, Yu R.
europepmc   +1 more source

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

Cancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu   +11 more
wiley   +1 more source

GRB2 promotes brain metastasis in HER2-positive breast cancer by regulating the Ras/MAPK pathway. [PDF]

Sci Rep
Li H, Zhang Y, Han X, Li B, Liu D, Sun G.   +5 more
europepmc   +1 more source

Protein Kinases as Mediators for miRNA Modulation of Neuropathic Pain. [PDF]

Cells
Chang L, Čok Z, Yu L.
europepmc   +1 more source

BRAF Targeting Across Solid Tumors: Molecular Aspects and Clinical Applications. [PDF]

Int J Mol Sci
Mechahougui H, Gutmans J, Gouasmi R, Smekens L, Friedlaender A.   +4 more
europepmc   +1 more source

Ras-MAPK pathway in patients with lupus nephritis. [PDF]

Lupus Sci Med
Zhang C, Jing X, Zhang Y, Jin Y, Gao X, Yu J, Liang D, Zhang J, Zhong Q, Zhang H, Liu Z.   +10 more
europepmc   +1 more source

Polystyrene nanoplastics exposure induces cognitive impairment in mice via induction of oxidative stress and ERK/MAPK-mediated neuronal cuproptosis. [PDF]

Part Fibre Toxicol
Chen Y, Nan Y, Xu L, Dai A, Orteg RMM, Ma M, Zeng Y, Li J.   +7 more
europepmc   +1 more source

Combined Omipalisib and MAPK Inhibition Suppress PDAC Growth. [PDF]

Cancers (Basel)
Bye BA, Jack JL, Pierce A, Walsh RM, Eades AE, Chalise P, Olou A, VanSaun MN.   +7 more
europepmc   +1 more source

Whole‐genome CRISPR‐Cas9 knockout screens identify SHOC2 as a genetic dependency in NRAS‐mutant melanoma

Cancer Communications, EarlyView.
Andrea Y. Gu, Tet Woo Lee, Aziza Khan, Xuenan Zhang, Francis W. Hunter, Dean C. Singleton, Stephen M. F. Jamieson   +6 more
wiley   +1 more source