Results 241 to 250 of about 449,479 (345)

PELI2 inhibits colorectal cancer development through MAPK signaling pathway. [PDF]

Mol Med
Liu J, Hu S, Zhao L, Yang Y, Wu G, Duan Y, Ma X, Wang P, Zhang Z, Zong H.   +9 more
europepmc   +1 more source

CXCL6 Reshapes Lipid Metabolism and Induces Neutrophil Extracellular Trap Formation in Cholangiocarcinoma Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
CXCL6's function in cholangiocarcinoma is underexplored. Here it is discovered that CXCL6 is upregulated in cholangiocarcinoma tissues and promotes proliferation and metastasis of it. CXCL6 functions through the CXCR1/2‐JAK‐STAT/PI3K axis and reshaping tumor lipid metabolism.
Tian He, Zi‐Yi Wang, Bin Xu, Cheng‐Jie Zhong, Lu‐Na Wang, Huan‐Chen Shi, Zi‐Yue Yang, Shi‐Qi Zhou, Hui Li, Bo Hu, Xiao‐Dong Zhu, Ying‐Hao Shen, Jian Zhou, Jia Fan, Hui‐Chuan Sun, Cheng Huang   +15 more
wiley   +1 more source

Hederacoside C Modulates EGF-Induced MUC5AC Mucin Gene Expression by Regulating the MAPK Signaling Pathway in Human Airway Epithelial Cells. [PDF]

Biomol Ther (Seoul)
Hossain R, Hossain MS, Lee HJ, Lee CJ.
europepmc   +1 more source

Sustained activation of Erk1/2 MAPK and cell growth suppression by the insert-negative, but not the insert-positive isoform of the human calcitonin receptor [PDF]

, 2000
LJ Raggatt, Andreas Evdokiou, D. Findlay
openalex   +1 more source

Gas Bubbles from Biodegradable Magnesium Implants Convey Mechanical Cues and Promote Immune Cell Stimulation

Advanced Science, EarlyView.
Bubbles in soft tissue are the unavoidable consequence of magnesium implant degradation in patients, yet their biological significance remains unclear. Using advanced imaging and spatial transcriptomics, this study reveals a pronounced inflammatory and mechanical response near bubbles, contrasting with pro‐regenerative events closer to the implant ...
Heithem Ben Amara, Jincy Philip, Omar Omar, Peter Thomsen   +3 more
wiley   +1 more source

Mechanisms of Erythropoietin-Mediated Protection Against Retinal Ganglion Cell Apoptosis. [PDF]

Med Sci Monit
Chen W, Lao W, Chen Y, Liang X.
europepmc   +1 more source

Magnetite Micro/Nanorobots for Efficient Targeted Alleviation of Inflammatory Bowel Disease

Advanced Science, EarlyView.
Improved reactive oxygen species scavenging capacities of functionalized micro/nanorobots (MNRs) are useful for the treatment of inflammatory bowel disease (IBD). MNRs can break the harmful bacteria in IBD, thereby eliminating inflammation and restoring the intestinal barrier function.
Ying Feng, Yang Liu, Linlin Liu, Qian Yang, Miao An, Huaming Yang   +5 more
wiley   +1 more source

RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors

Clinical Cancer Research, 2015
S. Loi, Sathana Dushyanthen, P. Beavis, R. Salgado, C. Denkert, P. Savas, Susan E. Combs, D. Rimm, J. Giltnane, M. V. Estrada, V. Sanchez, M. Sanders, R. Cook, M. Pilkinton, S. Mallal, Kai Wang, V. Miller, P. Stephens, R. Yelensky, Franco Doimi, H. Gómez, Sergey Ryzhov, P. Darcy, C. Arteaga, J. Balko   +24 more
semanticscholar   +1 more source

Impacts of high salt diet and cold stress on heat shock protein 27 and p 38 MAPK in myocardium of rats [PDF]

, 2000
Zhiming Zhu, Ziqian Wu, Xianmei Wang, Zhu Shan-jun, Hu Houxian, Haiyan Wang   +5 more
openalex   +1 more source

C1q+ Macrophage–Tumor Cell Interaction Promoted Tumorigenesis via GPR17/PI3K/AKT Pathway Induced DNA Hypermethylation in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
In the TME of NPC, C1q secreted by C1q+ TAMs interacted with GPR17 to activate PI3K/AKT signaling through strengthening GPR17 coupling PI3K and increasing calcium levels in tumor cells. The activated PI3K/AKT signaling further induces DNA hypermethylation to promote the malignancy and stemness of tumor cells.
Yunzhi Liu, Cuicui Huang, Min Luo, Wenfu Lu, Baifeng Zhang, Lu Bai, Shuyue Zheng, Yanan Tan, Shanshan Li, Huali Wang, Lanqi Gong, Xinyuan Guan   +11 more
wiley   +1 more source