Results 311 to 320 of about 449,479 (345)

The MAPK signaling cascade

The FASEB Journal, 1995
The transmission of extracellular signals into their intracellular targets is mediated by a network of interacting proteins that regulate a large number of cellular processes. Cumulative efforts from many laboratories over the past decade have allowed the elucidation of one such signaling mechanism, which involves activations of several membranal ...
Edwin G. Krebs, Rony Seger
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Rice MAPKs

Biochemical and Biophysical Research Communications, 2003
Mitogen-activated protein kinase (MAPK) cascades are evolutionary conserved from unicellular to complex eukaryotic organisms, and constitute one of the major signalling pathways involved in regulating a wide range of cellular activities from growth and development to cell death.
Ganesh K, Agrawal, Hitoshi, Iwahashi, Randeep, Rakwal   +2 more
openaire   +2 more sources

The Detection of MAPK Signaling

Current Protocols in Cell Biology, 2005
AbstractMitogen‐activated protein kinase (MAPK) cascades are central pathways that participate in the intracellular transmission of extracellular signals. Each of the MAPK signaling cascades seems to consist of three to five tiers of protein kinases that sequentially activate each other by phosphorylation.
Yoav D. Shaul, Rony Seger
openaire   +5 more sources

Multisite phosphorylation by MAPK

Science, 2016
Progressive phosphorylation controls the activity of a transcription ...
Whitmarsh, Alan J., Davis, Roger J.
openaire   +4 more sources

MAPK and memory

Trends in Neurosciences, 1999
We read with great interest the article by Orban et al.1xOrban, P.C., Chapman, P.F., and Brambilla, R. Trends Neurosci. 1999; 22: 38–44Abstract | Full Text | Full Text PDF | PubMed | Scopus (161)See all References1 because we too have recently found that the mitogen-activated protein kinase (MAPK) cascade is involved in the long-term memory of an ...
Roger Walz, Isabel Cristina Rockenbach, Rafael Roesler, Olavo B. Amaral, João Quevedo   +4 more
openaire   +2 more sources

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms.

Science, 1999
A mechanism by which the Ras-mitogen-activated protein kinase (MAPK) signaling pathway mediates growth factor-dependent cell survival was characterized. The MAPK-activated kinases, the Rsks, catalyzed the phosphorylation of the pro-apoptotic protein BAD ...
A. Bonni, A. Brunet, A. West, S. R. Datta, M. Takasu, M. Greenberg   +5 more
semanticscholar   +1 more source

Mechanisms and functions of p38 MAPK signalling.

Biochemical Journal, 2010
The p38 MAPK (mitogen-activated protein kinase) signalling pathway allows cells to interpret a wide range of external signals and respond appropriately by generating a plethora of different biological effects.
A. Cuadrado, A. Nebreda
semanticscholar   +1 more source

Analysis of MAPK Activities Using MAPK-Specific Antibodies

2014
Phosphorylation of proteins by mitogen-activated protein kinases is central to many cellular processes, including signal transduction after stress encounter. Thus, assays to identify or characterize MAP kinase activities are a key tool for research in this area. While in-gel kinase assays using isotope-labeled ATP are a powerful tool to investigate the
Daniel J. Haischer, Roland Willmann, Andrea A. Gust   +2 more
openaire   +3 more sources

RAS/MAPK signaling functions in oxidative stress, DNA damage response and cancer progression

Journal of Cellular Physiology, 2019
Mitogen‐activated protein kinase (MAPK) signaling pathways organize a great constitution network that regulates several physiological processes, like cell growth, differentiation, and apoptotic cell death.
Setareh Rezatabar, Ansar Karimian, V. Rameshknia, H. Parsian, M. Majidinia, Tayebeh Azramezani Kopi, A. Bishayee, A. Sadeghinia, M. Yousefi, Mohsen Monirialamdari, B. Yousefi   +10 more
semanticscholar   +1 more source