Results 331 to 340 of about 736,655 (384)

Stabilization of the MAPK-Epigenetic Signaling Axis Underlies the Protective Effect of Thyme Oil Against Cadmium Stress in Root Meristem Cells of <i>Vicia faba</i>. [PDF]

Int J Mol Sci
Gocek-Szczurtek N, Żabka A, Wróblewski M, Polit JT.   +3 more
europepmc   +1 more source

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

Microglia-derived neuroinflammatory pathways in neuropathic pain. [PDF]

Korean J Pain
Pu W, Zhou L, Liu R, Li S, Wang S, Cao S.   +5 more
europepmc   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Surfactin Inhibits Osteoclast Differentiation by Negatively Regulating the Elk1-AP-1-NFATc1 Axis. [PDF]

Biomedicines
Maruyama K, Koga A, Kodama Y, Yamasaki R, Nagai-Yoshioka Y, Miyamoto JJ, Kuroishi K, Gunjigake K, Kawamoto T, Ariyoshi W.   +9 more
europepmc   +1 more source

Microgravity activates monocyte ERK1/2 signaling and modulates the response to lipopolysaccharide. [PDF]

Mol Med
Mammadov RA, van Hulten MPC, Bakker MK, Verhaar AP, Peppelenbosch MP.   +4 more
europepmc   +1 more source

<i>MAP3K7CL</i> Inhibits the Inflammatory Responses in Goose Fatty Liver. [PDF]

J Poult Sci
Zhao M, Lv M, Li J, Fan X, Liu L, Gong D, Zhang Y.   +6 more
europepmc   +1 more source

Non-coding RNAs-mediated regulation of the MAPK pathway in gastric cancer: translational perspectives. [PDF]

Discov Oncol
Darmadi D, Aghazadeh-Habashi K, Ayvazyan S, Bozorgnia A, Khodabandehloo E.   +4 more
europepmc   +1 more source

Lycopene Protects Deoxynivalenol-Induced Intestinal Barrier Dysfunction and NLRP3 Inflammasome Activation by Targeting the ERK Pathway. [PDF]

Antioxidants (Basel)
Cai Z, Lu Z, Wang Y, Song W, Yang X, Zhang C.   +5 more
europepmc   +1 more source