Results 71 to 80 of about 178,432 (330)

Seasonal pulses of Marburg virus circulation in juvenile Rousettus aegyptiacus bats coincide with periods of increased risk of human infection. [PDF]

PLoS Pathogens, 2012
Marburg virus (family Filoviridae) causes sporadic outbreaks of severe hemorrhagic disease in sub-Saharan Africa. Bats have been implicated as likely natural reservoir hosts based most recently on an investigation of cases among miners infected in 2007 ...
Brian R Amman, Serena A Carroll, Zachary D Reed, Tara K Sealy, Stephen Balinandi, Robert Swanepoel, Alan Kemp, Bobbie Rae Erickson, James A Comer, Shelley Campbell, Deborah L Cannon, Marina L Khristova, Patrick Atimnedi, Christopher D Paddock, Rebekah J Kent Crockett, Timothy D Flietstra, Kelly L Warfield, Robert Unfer, Edward Katongole-Mbidde, Robert Downing, Jordan W Tappero, Sherif R Zaki, Pierre E Rollin, Thomas G Ksiazek, Stuart T Nichol, Jonathan S Towner   +25 more
doaj   +1 more source

Presence and persistence of Ebola or Marburg virus in patients and survivors: A rapid systematic review [PDF]

, 2016
Background: The 2013-15 Ebola outbreak was unprecedented due to sustainedtransmission within urban environments and thousands of survivors. In 2014 the World Health Organization stated that there was insufficient evidence to give definitive guidance ...
Brainard, Julii, Edmunds, Kelly, Hooper, Lee, Hunter, Paul, Pond, Katherine   +4 more
core   +3 more sources

Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Ebola, Sudan, Marburg and Lassa viruse

PLoS Pathogens
Viral haemorrhagic fevers (VHF) pose a significant threat to human health. In recent years, VHF outbreaks caused by Ebola, Marburg and Lassa viruses have caused substantial morbidity and mortality in West and Central Africa.
A. Flaxman, Sarah Sebastian, Sofia Appelberg, Kuan M Cha, M. Ulaszewska, Jyothi N. Purushotham, Ciarán Gilbride, Hannah Sharpe, Alexandra J. Spencer, S. Bibi, Daniel Wright, I. Schmidt, S. Dowall, L. Easterbrook, Stephen Findlay-Wilson, Sarah C. Gilbert, A. Mirazimi, T. Lambe   +17 more
semanticscholar   +1 more source

Drivers of African Filovirus (Ebola and Marburg) Outbreaks

Vector Borne and Zoonotic Diseases, 2022
Outbreaks of African filoviruses often have high mortality, including more than 11,000 deaths among 28,562 cases during the West Africa Ebola outbreak of 2014–2016.
P. Stephens, Mekala Sundaram, Susana Ferreira, N. Gottdenker, Kaniz Fatema Nipa, A. M. Schatz, J. Schmidt, J. Drake   +7 more
semanticscholar   +1 more source

Beyond the Edge: Charge‐Transfer Excitons in Organic Donor‐Acceptor Cocrystals

Advanced Functional Materials, EarlyView.
Complex excitonic landscapes in acene–perfluoroacene cocrystals are unveiled by polarization‐resolved optical spectroscopy and many‐body theory. This systematic study of a prototypical model system for weakly interacting donor–acceptor compounds challenges common views of charge‐transfer excitons, providing a refined conceptual framework for ...
Sebastian Anhäuser, Ana M. Valencia, Sergei I. Ivlev, Marc Zeplichal, Andreas Terfort, Caterina Cocchi, Gregor Witte   +6 more
wiley   +1 more source

A novel MARV glycoprotein-specific antibody with potentials of broad-spectrum neutralization to filovirus

eLife
Marburg virus (MARV) is one of the filovirus species that cause deadly hemorrhagic fever in humans, with mortality rates up to 90%. Neutralizing antibodies represent ideal candidates to prevent or treat virus disease.
Yuting Zhang, Min Zhang, Haiyan Wu, Xinwei Wang, Hang Zheng, Junjuan Feng, Jing Wang, Longlong Luo, He Xiao, Chunxia Qiao, Xinying Li, Yuanqiang Zheng, Weijin Huang, Youchun Wang, Yi Wang, Yanchun Shi, Jiannan Feng, Guojiang Chen   +17 more
doaj   +1 more source

Marburg virus infection detected in a common African bat. [PDF]

PLoS ONE, 2007
Marburg and Ebola viruses can cause large hemorrhagic fever (HF) outbreaks with high case fatality (80-90%) in human and great apes. Identification of the natural reservoir of these viruses is one of the most important topics in this field and a ...
Jonathan S Towner, Xavier Pourrut, César G Albariño, Chimène Nze Nkogue, Brian H Bird, Gilda Grard, Thomas G Ksiazek, Jean-Paul Gonzalez, Stuart T Nichol, Eric M Leroy   +9 more
doaj   +1 more source

Combination therapy protects macaques against advanced Marburg virus disease

Nature Communications, 2021
Monoclonal antibodies (mAbs) and remdesivir, a small-molecule antiviral, are promising monotherapies for many viruses, including members of the genera Marburgvirus and Ebolavirus (family Filoviridae), and more recently, SARS-CoV-2.
R. Cross, Z. Bornholdt, A. Prasad, V. Borisevich, K. Agans, D. Deer, Dafna M. Abelson, Do H. Kim, W. Shestowsky, L. Campbell, Elaine Bunyan, J. Geisbert, Karla A. Fenton, L. Zeitlin, D. Porter, T. Geisbert   +15 more
semanticscholar   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

Advanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer, Dolores J. Salander, Witold Szymanski, Johannes Graumann, Yukai Wang, Kai Zhao, Jörg W. Bartsch, María Gómez‐Serrano, Daniel Bachurski, Silke Reinartz, Elke von Pogge von Strandmann   +10 more
wiley   +1 more source

Serosurvey on Household Contacts of Marburg Hemorrhagic Fever Patients

Emerging Infectious Diseases, 2006
The first major outbreak of Marburg hemorrhagic fever (MHF) outside a laboratory environment occurred in the subdistrict of Watsa, Democratic Republic of Congo, from October 1998 to August 2000.
Matthias Borchert, Sabue Mulangu, Robert Swanepoel, Modeste Lifenya Libande, Antoine Tshomba, Amayo Kulidri, Jean-Jacques Muyembe-Tamfum, Patrick Van der Stuyft   +7 more
doaj   +1 more source