Results 161 to 170 of about 849,516 (245)
Genetic Contribution to Asthma Informs Acute Chest Syndrome Pathophysiology and Risk Stratification
American Journal of Hematology, EarlyView.ABSTRACT Acute chest syndrome (ACS) is a severe complication of sickle cell disease (SCD) occurring in ~50% of patients, some presenting frequent episodes. We lack tools to identify patients at high risk of ACS occurrence or frequent episodes. Epidemiological studies have found an association between asthma and ACS, but whether this link is causal is ...
Sara El Aouhel +10 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt +9 more
wiley +1 more source
On the Prospects for African Philosophy in Australia
Australian Journal of Social Issues, EarlyView.ABSTRACT This paper grapples with the situation of people of African descent in Australia by working through the constitution of the body of academic philosophy in the country. It contends with the parochialism of the Australian philosophical community and the prospects for the cultivation of greater pluralism. Taking African philosophy as one possible
Bryan Mukandi
wiley +1 more source
Angewandte Chemie, EarlyView.Electrochemical measurements as single aqueous microdroplets collide with electrode interfaces reveal nanoscale wetting dynamics. By tuning electrostatic repulsion, we control contact formation and probe surface interactions well beyond the optical diffraction limit.
Kathryn J. Vannoy +2 more
wiley +2 more sources
Molecular Characterization and Pathogenicity of a Novel Recombinant NADC30-Like PRRSV Strain Isolated From Piglets Inducing Intestinal Inflammation, and Construction of Its Infectious Clone. [PDF]
Transbound Emerg DisLin Y +13 more
europepmc +1 more source
Dupilumab Beyond the Airway: Decreased Morbidity in a Real‐World Analysis
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Post hoc analyses of clinical trials have characterized dupilumab's adverse effects, yet the real‐world impact in chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma is not well described. This study aims to characterize the risks of lymphoma, cardiovascular events, eosinophilia, joint pain, inflammatory arthritis, and ...
Emma J. Anisman +9 more
wiley +1 more source
Publisher Correction: argeting of HIF2-driven cachexia in kidney cancer. [PDF]
Nat MedAbu-Remaileh M +19 more
europepmc +1 more source
Annals of Neurology, EarlyView.Objective Clinically relevant Alzheimer's disease co‐pathology is common in Lewy body disorders. Plasma P‐tau217 is a sensitive biomarker for amyloid and tau pathology in Alzheimer's disease. The objective was to determine if plasma P‐tau217 associates with Alzheimer's disease co‐pathology and cognition in Lewy body disorders. Methods Participants had (
Thomas F. Tropea +20 more
wiley +1 more source
Synthesis of Conjugated Linear and Cyclic Polyynes by Selective Alkyne Metathesis
Angewandte Chemie, EarlyView.The formation of polyynes with an odd number of conjugated triple bonds is challenging, particularly for complex architectures since most established methods rely on irreversible C–C bond‐forming reactions. To address this, we have developed the synthesis of triynes via alkyne metathesis.
Julien Escudero +12 more
wiley +2 more sources
Angewandte Chemie, EarlyView.By exploiting the structural benefits of PHI, we synthesized CoPHI with atomically dispersed cobalt sites at high density. This architecture enables efficient nitrate ion adsorption, promotes water dissociation, and enhances *H generation on the catalyst surface, thereby significantly improving electrochemical nitrate reduction performance.
Nana Gao +14 more
wiley +2 more sources