Results 171 to 180 of about 101,584 (254)

CO2‐to‐CO Electrochemical Conversion With an Fe(I) Porphyrin Complex in Water

Angewandte Chemie, EarlyView.
Using in situ UV–vis/IR spectroelectrochemistry, we track CO2 reduction by a water‐soluble iron porphyrin. Rather than the usual [Fe0] intermediate in organic solvents, CO2 binds the electrogenerated [FeI] species and undergoes reductive C─O cleavage to stable [FeII‐CO]. This previously unexplored reaction pathway is facilitated by an aqueous H‐bonding
Andrew Howe, Aude Salamé, Ulysse Garnier, Marc Robert, Elodie Anxolabéhère‐Mallart, Mun Hon Cheah   +5 more
wiley   +2 more sources

A Modular Synthesis of C5‐Sulfenyl Thiazoles via an Intermolecular Pummerer Rearrangement: An Underexplored Scaffold for Medicinal Chemistry

Angewandte Chemie, EarlyView.
Modular access to underexplored C5‐sulfenyl thiazoles via an intermolecular Pummerer rearrangement is reported. The methodology exhibits a broad functional group tolerance enabling the seamless design of trisubstituted thiazole cores bearing a sulfur handle for further elaboration.
Joe L. Smy, Theo C. Webb, Barnaby W. Greenland, S. Mark Roe, John Spencer, Storm Hassell‐Hart   +5 more
wiley   +2 more sources

Overuse of a molecular infectious diarrhea panel in acute care: an opportunity for diagnostic stewardship. [PDF]

Antimicrob Steward Healthc Epidemiol
Alhothli B, Payne M, Stefanovic A, Leung V, Lowe CF, Tang P, Romney MG, Matic N.   +7 more
europepmc   +1 more source

Glutathione‐Responsive Acyl‐Modifications for Targeted RNA Decaging and Prolonged Protein Synthesis

Angewandte Chemie, EarlyView.
The self‐immolation of disulfide‐based mRNA modifications in response to endogenous glutathione (GSH) promotes a gradual release of translatable mRNA within the cell, leading to improved nuclease resistance, tunable release properties, and a significant increase (up to 600%) of target protein production over time. This strategy offers an exciting proof
Mary E. Flood, Sathishkumar Kurusamy, Mark Berney, C. Mark Smales, Elizabeth M. Topp, Joanna F. McGouran, Steven Ferguson   +6 more
wiley   +2 more sources

Automated Cardiac Arrest Detection Using Wrist-Worn Photoplethysmography: External Validation in Patients With Induced Shockable Cardiac Arrest (DETECT-1b). [PDF]

Circ Arrhythm Electrophysiol
Edgar R, Scholte NTB, Ebrahimkheil K, Jansen CE, Beukema RJ, Brouwer MA, Yap SC, Mafi-Rad M, Knops RE, Ronner E, Cetinyurek-Yavuz A, Vernooy K, Boersma E, Stas PC, van Royen N, Bonnes JL.   +15 more
europepmc   +1 more source

Proteome‐Wide Target Identification Using Reactive Metallo‐Scaffolds (r‐mS): A Platform for Metallodrug Discovery

Angewandte Chemie, EarlyView.
Re‐envisioning the Ligandable Proteome: Reactive Metallo‐Scaffolds (r‐mS) combine non‐covalent protein engagement by a metallo‐scaffold with covalent cysteine capture through a tethered chloroacetamide warhead. Chemoproteomic profiling reveals unique enzyme engagement including ligases, kinases and methyltransferases, highlighting opportunities for ...
Jessica E. Waters, Harry Wilders, George S. Biggs, Mika Kintzel, Emma E. Cawood, Jonathan Bailey, Sarah Maslen, Yew Mun Yip, Mason Wakley, Ioannis G. Riziotis, Thomas W. Rees, Joanna Redmond, J. Mark Skehel, David House, Jacob Bush, Jeannine Hess   +15 more
wiley   +2 more sources

Correction: Efficacy of dual triggering in poor ovarian responders defined according to Bologna and POSEIDON criteria: a systematic review with meta-analysis. [PDF]

J Assist Reprod Genet
Mercorio A, Conforti A, Pluchino N, Drakopoulos P, Giudice M, Giampaolino P, Vallee A, Tokgoz VY, Alviggi C, Ayoubi JM.   +9 more
europepmc   +1 more source

Tenosynovial and Transverse Carpal Ligament Biopsy for Early Transthyretin Amyloidosis Cardiomyopathy Detection: A Systematic Review and African American Retrospective Cohort Study. [PDF]

J Hand Surg Glob Online
Dogar S, Punnakanta P, Williams MD, Hamda YA, Songcharoen S, Dodson MA, Walker ME.   +6 more
europepmc   +1 more source

Sodium Copper Chlorophyllin Inhibits Porcine Reproductive and Respiratory Syndrome Virus Infection Through Multiple Antiviral Mechanisms. [PDF]

Transbound Emerg Dis
Wang X, Zhang J, Rui L, Zhu J, Yan N, Jia M, Zhang L, Fu L, Wang Y.   +8 more
europepmc   +1 more source

Polygenic scores in the diagnosis of abnormal complete blood count values. [PDF]

Hemasphere
Srour M, Lecluze E, Chacowry E, Saby M, Pincez T.   +4 more
europepmc   +1 more source