Results 161 to 170 of about 101,584 (254)

Microenvironment Engineering as a Design Principle for Suppressing Catalyst Metal Loss

open access: yesAngewandte Chemie, EarlyView.
Under ionomer‐containing microenvironments, nonporous carbon supports enhance the retention of dissolved platinum ions, whereas porous carbon supports promote pore‐confined redeposition and mitigate net platinum loss. ABSTRACT Stability losses in platinum electrocatalysts arise from dissolution, redeposition, and restructuring processes that are ...
Sumin Lim   +4 more
wiley   +2 more sources

Genetic Modifiers of ABCA1 Activity Interact with APOE Isoforms to Mediate Alzheimer's Disease Risk

open access: yesAnnals of Neurology, EarlyView.
Objective ATP‐binding cassette transporter A1 (ABCA1) has been associated with Alzheimer's disease (AD), but the mechanisms by which it impacts disease risk are unknown. ABCA1 is known to bind apolipoprotein E (ApoE) and catalyze apolipoprotein lipidation.
Andrés Peña‐Tauber   +24 more
wiley   +1 more source

Farnesyltransferase Enables Modular Assembly of Dual‐Functional Nanobody Conjugates for in Vivo Imaging of Inflammation

open access: yesAngewandte Chemie, EarlyView.
A modular farnesyltransferase‐based chemoenzymatic platform enables fast, site‐specific labeling of nanobodies for PET imaging of inflammation. CD11b‐targeted PET agents selectively image myeloid‐driven inflammation, while CD45‐targeted PET agents provide sensitive whole‐body immune mapping.
Sneha Venkatachalapathy   +7 more
wiley   +2 more sources

Regional and Compartmental Changes Drive Progressive Patterns of Striatal Degeneration in X‐Linked Dystonia Parkinsonism

open access: yesAnnals of Neurology, EarlyView.
Objective Initially described in 1976, X‐linked dystonia parkinsonism (XDP) is a neurodegenerative disease that can be characterized by the presentation of dystonia and parkinsonism symptoms. Although this disease bears some resemblance to other neurodegenerative diseases in terms of symptomatology, the pathological signature of XDP is still unclear ...
Adelie Y.S. Tan   +19 more
wiley   +1 more source

Optimizing oral contraceptive timing: Daytime intake reduces doses and enhances efficacy. [PDF]

open access: yesPLoS Comput Biol
Gavina BL   +6 more
europepmc   +1 more source

Neurotransmitter‐Defined Degeneration Patterns in Sporadic and C9orf72‐Associated Amyotrophic Lateral Sclerosis: Predilection to GABAergic, Serotonergic, Opioid, Glutamatergic, Endocannabinoid, and Microglial Systems—Implications for Therapy Development

open access: yesAnnals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl   +10 more
wiley   +1 more source

Step‐Associated Cu‐Ceria Interfaces Enhance Catalytic Activity and Selectivity

open access: yesAngewandte Chemie, EarlyView.
The catalytic activity and selectivity of supported Cu nanoparticles depends on their interfacial environments, with Cu nanoparticles at step‐associated environments converting CO2 to methanol much faster than those on terrace facets, indicating that step sites create more active metal–oxide interfaces.
Shuxuan Feng   +12 more
wiley   +2 more sources

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