Results 31 to 40 of about 52,425 (235)

Generation of A Triple Insert Live Avian Herpesvirus Vectored Vaccine Using CRISPR/Cas9-Based Gene Editing

open access: yesVaccines, 2020
Herpesvirus of turkeys (HVT), used originally as a vaccine against Marek’s disease (MD), has recently been shown to be a highly effective viral vector for generation of recombinant vaccines that deliver protective antigens of other avian pathogens.
Na Tang   +6 more
doaj   +1 more source

Plasma proteomic profiling and molecular clustering reveal immune-defined prognostic subtypes in lung adenocarcinoma. [PDF]

open access: yesInt J Cancer
What's new? Lung adenocarcinoma shows considerable heterogeneity in disease progression and therapeutic response. Here, the authors analyzed tumor samples through proteomic profiling and applied network‐based clustering. They identified two distinct patient groups with different demographic, clinical, and molecular characteristics.
Neogi U   +10 more
europepmc   +2 more sources

Habitus or the Possibility of Science of the Contingent [PDF]

open access: yes, 2015
Numer został przygotowany przy wsparciu Ministerstwa Nauki i Szkolnictwa Wyższego (1222/P-DUN/2015).Most of sciences can be traced back to Aristotle. This is because in opposition to Plato he was able to find a way in which one could give a scientific ...
Gensler, Marek
core  

Spatial judgment in Parkinson's disease: Contributions of attentional and executive dysfunction [PDF]

open access: yes, 2019
Spatial judgment is impaired in Parkinson's disease (PD), with previous research suggesting that disruptions in attention and executive function are likely contributors.
Cronin-Golomb, Alice   +3 more
core   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

open access: yesAnimal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang   +10 more
wiley   +1 more source

High Accuracy Classification of Parkinson's Disease through Shape Analysis and Surface Fitting in $^{123}$I-Ioflupane SPECT Imaging

open access: yes, 2017
Early and accurate identification of parkinsonian syndromes (PS) involving presynaptic degeneration from non-degenerative variants such as Scans Without Evidence of Dopaminergic Deficit (SWEDD) and tremor disorders, is important for effective patient ...
Ghosh, Shantanu   +3 more
core   +1 more source

Improved Cardiorespiratory Fitness Is Associated with Increased Cortical Thickness in Mild Cognitive Impairment [PDF]

open access: yes, 2015
Cortical atrophy is a biomarker of Alzheimer’s disease (AD) that correlates with clinical symptoms. This study examined changes in cortical thickness from before to after an exercise intervention in mild cognitive impairment (MCI) and healthy elders ...
Alfini, Alfonso J.   +5 more
core   +2 more sources

PERCC1‐associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide

open access: yesJPGN Reports, EarlyView.
Abstract Congenital diarrheas and enteropathies (CODE) are rare inherited disorders characterized by early‐onset intractable diarrhea. Though progress has been made in elucidating the genetic basis of CODE, much remains to be discovered. Another challenge is the lack of curative therapies—treatment is primarily supportive including enteral and ...
Angela Tran, Vivien Nguyen, Phuong Huynh
wiley   +1 more source

Genetic variation associated with Marek’s disease resistance and susceptibility in white leghorn chickens

open access: yesPoultry Science
Despite of effective control by vaccination, Marek’s disease virus (MDV) remains a significant threat to poultry health and productivity due to continued virus evolution, which drives the need to better understand host genetic factors underlying the ...
Christos Dadousis   +8 more
doaj   +1 more source

A plea to implement robustness into a breeding goal: poultry as an example [PDF]

open access: yes, 2008
The combination of breeding for increased production and the intensification of housing conditions have resulted in increased occurrence of behavioral, physiological, and immunological disorders.
Brom, F.W.A.   +3 more
core   +2 more sources

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