Results 31 to 40 of about 66,260 (210)

Comparative evaluation of effects of bleaching on color stability and marginal adaptation of discolored direct and indirect composite laminate veneers under in vivo conditions

The Journal of Indian Prosthodontic Society, 2015
Statement of Problem: Change in color and loss of marginal adaptation of tooth colored restorative materials is not acceptable. Bleaching is commonly used for treating discolored teeth.
Veena Jain, Taposh K Das, Gunjan Pruthi, Naseem Shah, Suresh Rajendiran   +4 more
doaj   +1 more source

Root dentin surface activation to improve bioceramic bonding: Ascanning electron microscopic study [PDF]

Journal of Dental Research, Dental Clinics, Dental Prospects, 2020
Background. Bioceramics need to interact chemically with dentin to exhibit adequate bioactivity.Proper bonding of bioceramics with dentin is of considerable importance.
Shazeena Qaiser, Mithra N. Hegde, Darshana Devadiga, Mahalaxmi Yelapure   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Digital workflow impact on CAD/CAM crown accuracy: a five-protocol comparison

Brazilian Dental Science
Objective: The objective of this in-vitro study was to assess and compare the marginal adaptation and internal fit of zirconia-reinforced lithium silicate (ZLS) ceramic crowns produced utilising five distinct digital protocols that include multiple ...
Heba Ismail, Seif Elgayar, Ahmad Aboelfadl, Tarek Salah, Nancy Rafla   +4 more
doaj   +1 more source

Evaluation of Marginal Fit of Provisional Restoration Fabricated Using Tooth Moulding Acrylic Powder, Bisacryl Composite and 3D Printed Resin: An In-vitro Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Provisional restorations should have a good marginal fit with non impinging margins and ease of cleansability to protect the gingiva and periodontal tissues.
Priyanka Gopalakrishnan, Mathew Chalakuzhiyil Abraham, N Vidhyasankari, Sakthi Gnanavel Shanmugam, Vishnupriya Venkatasubramanian, Sindhuja Nagarajan   +5 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

The evaluation and comparison of marginal adaptation in metal ceramic and all ceramic restorations fabricated by two methods: CAD/CAM and conventional [PDF]

Journal of Dental Materials and Techniques, 2018
Introduction: Marginal fit is a key factor for long term clinical success through any dental restorations. Poor marginal adaptation causes cement dissolution.
Ahmad Ghahremanloo, Mohsen Movahedzadeh, Abdollah Javan Rashid   +2 more
doaj   +1 more source