Results 51 to 60 of about 59,702 (259)

Evaluation of marginal and internal adaptation of implant-supported PEEK crowns fabricated by 3D printing, milling, and pressing: a micro-CT analysis

open access: yesBMC Oral Health
Objectives This study aimed to evaluate and compare the marginal adaptation and internal gap of implant-supported crowns fabricated from polyetheretherketone (PEEK) using CAD-CAM milling, heat pressing, and 3D printing, employing non-destructive micro ...
Aliaa Ibrahim Mahrous   +6 more
doaj   +1 more source

Comparative Evaluation of Microleakage Between Nano-Ionomer, Giomer and Resin Modified Glass Ionomer Cement in Class V Cavities- CLSM Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Marginal integrity of adhesive restorative materials provides better sealing ability for enamel and dentin and plays an important role in success of restoration in Class V cavities.
Indira Priyadarshini Bollu   +7 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Impact of finish line designs on the adaptation of ceramic fixed dental prostheses: a systematic review and network meta-analysis

open access: yesBMC Oral Health
Background Insufficient marginal and internal adaptation can lead to secondary caries, pulp infection, periodontal disease, and tooth loss. This network meta-analysis (NMA) assessed the impact of various finish line designs on the marginal and internal ...
Adrienn Pál   +9 more
doaj   +1 more source

Deep Ranking with Adaptive Margin Triplet Loss

open access: yesCoRR, 2021
We propose a simple modification from a fixed margin triplet loss to an adaptive margin triplet loss. While the original triplet loss is used widely in classification problems such as face recognition, face re-identification and fine-grained similarity, our proposed loss is well suited for rating datasets in which the ratings are continuous values.
Mai Lan Ha, Volker Blanz
openaire   +2 more sources

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Marginal Seating of Zirconium Monolithic Crown Restorations Utilising Different Types of Luting Agents - A Comparative Study

open access: yesIndian Journal of Dental Research
Background: Marginal adaptation plays a critical role in the clinical success of ceramic inlays, and several factors, including the type and composition of luting cement, can influence the marginal fit and overall integrity of restorations.
Zahraa M. Al-Hawwaz   +3 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

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