Results 51 to 60 of about 9,847,554 (308)
Inequality and Total Effect Summary Measures for Nominal and Ordinal Variables
Sociological ScienceMany of the topics most central to the social sciences involve nominal groupings or ordinal rankings. There are many cases in which a summary of a nominal or ordinal independent variable's effect, or the effect on a nominal or ordinal outcome, is needed ...
Trenton D. Mize, Bing Han
doaj +1 more source
Long-tail Detection with Effective Class-Margins
, 2022 ECCV 2022 Oral.
Jang Hyun Cho, Philipp Krähenbühl
openaire +3 more sources
Marginal Structural Models with Counterfactual Effect Modifiers [PDF]
The International Journal of Biostatistics, 2018 Abstract In health and social sciences, research questions often involve systematic assessment of the modification of treatment causal effect by patient characteristics. In longitudinal settings, time-varying or post-intervention effect modifiers are also of interest.
Zheng, Wenjing +2 more
openaire +3 more sources
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Rotation effects on the target-volume margin determination [PDF]
Physica Medica, 2015 Rotational setup errors are usually neglected in most clinical centers. An analytical formula is developed to determine the extra margin between clinical target volume (CTV) and planning target volume (PTV) to account for setup errors. The proposed formula corrects for both translational and rotational setup errors and then incorporated into margin ...
Zhang, Qinghui +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
A robust model-free approach for rare variants association studies incorporating gene-gene and gene-environmental interactions. [PDF]
PLoS ONE, 2013 Recently more and more evidence suggest that rare variants with much lower minor allele frequencies play significant roles in disease etiology. Advances in next-generation sequencing technologies will lead to many more rare variants association studies ...
Ruixue Fan, Shaw-Hwa Lo
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source