Results 201 to 210 of about 1,982,933 (271)

CAFs‐mediated histone lactylation reprograms cholesterol metabolism in colorectal cancer to drive CD8+ T cell immunosuppression

The Journal of Pathology, EarlyView.
Abstract The progression of colorectal cancer (CRC) is critically regulated by cancer‐associated fibroblasts (CAFs) within the tumor microenvironment (TME), yet the specific molecular mechanisms by which CAFs influence CRC remain unclear. This study reveals the mechanism by which CAFs promote CRC malignant progression and immune suppression through ...
Huachi Li, Jun Hu, Lei Huang, Zihao Wang, Haoran Tao, Feng Cao, Min Xie   +6 more
wiley   +1 more source

The evolution of liver graft preservation strategies in liver transplantation. [PDF]

Hepatobiliary Surg Nutr
Gao W, Song JL, Huang S, Cai ZY, Duan ZY, Xu X, Jin C, Lv T, Xu G, Yang JY.   +9 more
europepmc   +1 more source

Evaluating Testability of Permafrost Models Through Physical and Thermal Testing in Complex Mountain Terrain, Yukon, Canada

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT Due to its subsurface nature, permafrost cannot be directly observed with the naked eye or optical remote sensing. Consequently, accurately describing its distribution and thermal state is challenging. This is especially true in vast, remote environments, where obtaining comprehensive field data is demanding or improbable.
Ria Nicholson, Philip P. Bonnaventure, Nick C. Noad, Madeleine C. Garibaldi, Rabecca Thiessen, Will Kochtitzky   +5 more
wiley   +1 more source

A comparison of shot selection and goal scoring between collegiate and professional women's and men's ice hockey. [PDF]

Front Sports Act Living
Csiernik B, Cavell M, Nauboris K, Wattie N.   +3 more
europepmc   +1 more source

Repeated Pleistocene Permafrost Episodes in the Western Pannonian Basin

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT Concerning the study of past periglacial processes, the Pannonian Basin is a key area as it contains the southernmost frost polygons found in Central Europe. The presence or absence of permafrost is still, however, a matter of debate, and data on the timing of frost action are also scarce.
Krisztina Sebe, Ágnes Novothny, Gergely Surányi, Barbara Varga, László Fodor, Gábor Csillag   +5 more
wiley   +1 more source

Bulk delivery of a preassembled apical surface initiates epithelial lumen formation. [PDF]

Nat Commun
Ghosh S, Martin E, Chen Y, Amiera N, Singh S, Low KE, Girardello R, Hübner B, Dittmar G, Ludwig A.   +9 more
europepmc   +1 more source

Internal Structure, Kinematics, and Prehistory of Frozen Debris Lobe‐A (FDL‐A), Brooks Range, Alaska

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT Frozen Debris Lobe‐A (FDL‐A)—one of hundreds of FDLs in the Brooks Range of northern Alaska—is a slow‐moving landslide in permafrost that has been the subject of research since 2008 due to its close proximity to the Dalton Highway. Here, we synthesize more than a decade's worth of climate and surface measurements of monitored FDLs, and the ...
Margaret M. Darrow, Esther L. Babcock, Ben A. Leshchinsky   +2 more
wiley   +1 more source

Southern Ocean regime shift: divergent trends in surface phytoplankton community composition using a diagnostic pigment framework. [PDF]

Nat Commun
Adroli N, Hayward A, Strutton P, Ellwood M.   +3 more
europepmc   +1 more source

Internal Permafrost Structure of Geomorphologically Distinct Palsas in Northern Sweden Revealed by Quasi‐3D ERT

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT Permafrost in northern peatlands occurs within individual palsas or extensive peat plateaus and controls local carbon storage. These permafrost landforms are complex, and their internal structure remains poorly understood. We used quasi‐3D electrical resistivity tomography (ERT) measurements, supported by UAV‐LiDAR topography, frost probing ...
Cas Renette, Mirko Pavoni, Mauricio Fuentes, Erik Sturkell, Mats Olvmo, Heather Reese   +5 more
wiley   +1 more source

Integrating SfM, LiDAR and TLS for High‐Resolution Monitoring of Palsa Surface Changes and Degradation Dynamics

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT Understanding fine‐scale surface changes is crucial for quantifying ecosystem dynamics and detecting landscape changes. Palsas, comparably small peatland elevations with an ice‐rich permafrost core, undergo natural cycles of growth and degradation. They can also serve as indicators of climate change in subarctic regions. Because they typically
Alexander Störmer, Timo Kumpula, Pasi Korpelainen, Benjamin Burkhard   +3 more
wiley   +1 more source