Results 81 to 90 of about 17,919,150 (332)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Mental health in myasthenia gravis patients and its impact on caregiver burden

open access: yesScientific Reports, 2022
Psychiatric comorbidities are relevant in patients with Myasthenia gravis (MG). Also, MG patients experience a reduced health-related quality of life (HRQoL).
Derin Marbin   +4 more
doaj   +1 more source

G-computation of average treatment effects on the treated and the untreated

open access: yesBMC Medical Research Methodology, 2017
BackgroundAverage treatment effects on the treated (ATT) and the untreated (ATU) are useful when there is interest in: the evaluation of the effects of treatments or interventions on those who received them, the presence of treatment heterogeneity, or ...
Aolin Wang, R. Nianogo, O. Arah
semanticscholar   +1 more source

Multicell Experiments for Marginal Treatment Effect Estimation of Digital Ads

open access: yesManagement Science
Randomized experiments with treatment and control groups are an important tool to measure the impacts of interventions. However, in experimental settings with one-sided noncompliance extant empirical approaches may not produce the estimands a decision maker needs to solve the problem of interest.
Caio Waisman, Brett R. Gordon
openaire   +3 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

The treatment effects on the decision to steal: Marginal effects probit estimator.

open access: yes, 2023
The treatment effects on the decision to steal: Marginal effects probit estimator.
Nattavudh Powdthavee (7455494)   +3 more
core   +1 more source

Maximin Projection Learning for Optimal Treatment Decision with Heterogeneous Individualized Treatment Effects

open access: yesJournal of The Royal Statistical Society Series B-statistical Methodology, 2018
A salient feature of data from clinical trials and medical studies is inhomogeneity. Patients not only differ in baseline characteristics, but also in the way that they respond to treatment.
Cheng-Chun Shi   +3 more
semanticscholar   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Comparison of the Influence of Crown to Implant Ratio on Marginal Bone Loss around Implants in Posterior Areas of the Maxilla and Mandible

open access: yesپزشکی بالینی ابن سینا, 2016
Introduction & Objective: Due to the patients’ growing interest in the use of dental implants, medical staff should be completely aware of treatment success and prognostic factors to prevent failures.
M. Khoshhal   +3 more
doaj  

Comparison of three approaches for treating the bony access window in lateral sinus floor elevation: a retrospective analysis

open access: yesScientific Reports
The aim of this study was to retrospectively determine the effects of applying different treatment methods to the bony access window on the healing outcomes in lateral sinus floor elevation (SFE).
Won-Bae Park   +5 more
doaj   +1 more source

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