Results 51 to 60 of about 38,433 (267)

Small B Cell Non-Hodgkins Lymphoma in Pakistan [PDF]

, 2006
Objective: To study the pattern of small B cell lymphomas in Pakistan. Methods: This descriptive study was carried out at the Aga Khan University Hospital pathology department including 1721 cases of Non-Hodgkins Lymphoma (NHL) diagnosed during a period ...
Aftab, Kanwal, Bhurgri, Yasmin, Pervez, Shahid   +2 more
core   +1 more source

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Primary cutaneous marginal zone B cell lymphoma of the face: A challenging diagnosis [PDF]

, 2012
The primary cutaneous marginal zone B cell lymphoma is a small B cell lymphoma, including cells of the marginal zone, lymphoplasmacytic cells, and plasma cells.
Alves, R., Caetano, M., Lima, M., Oliveira, A., Selores, M.   +4 more
core  

A genome-wide association study of marginal zone lymphoma shows association to the HLA region [PDF]

, 2014
Marginal zone lymphoma (MZL) is the third most common subtype of B-cell non-Hodgkin lymphoma. Here we perform a two-stage GWAS of 1,281 MZL cases and 7,127 controls of European ancestry and identify two independent loci near BTNL2 (rs9461741, P=3.95 × 10−
Adami, H-O, Albanes, D, Ansell, SM, Armstrong, BK, Becker, N, Benavente, Y, Berndt, SI, Bertrand, KA, Birmann, BM, Boffetta, P, Bracci, PM, Brennan, P, Brooks-Wilson, AR, Burdett, L, Cerhan, JR, Chanock, SJ, Chiu, BCH, Chung, CC, Clavel, J, Conde, L, Corines, M, Cozen, W, De Bakker, PIW, De Roos, AJ, De Sanjose, S, Diver, WR, Dogan, A, Ennas, MG, Ferri, GM, Foretova, L, Fraumeni, JF, Giles, GG, Giovannucci, E, Glimelius, B, Gu, J, Habermann, TM, Hartge, P, Hjalgrim, H, Holford, TR, Holly, EA, Huang, J, Hutchinson, A, Jackson, RD, Kane, E, Kelly, RS, Kraft, P, Kricker, A, Lan, Q, Lawrence, C, Liang, L, Liebow, M, Lightfoot, T, Link, BK, Ma, B, Maria, A, Maynadie, M, Mckay, J, Melbye, M, Miligi, L, Monnereau, A, Montalvan, R, Morton, LM, Nieters, A, North, KE, Novak, AJ, Offit, K, Portlock, C, Purdue, MP, Riby, J, Ricco, R, Roman, E, Rothman, N, Severi, G, Severson, RK, Skibola, CF, Slager, SL, Smedby, KE, Smith, A, Smith, MT, Spinelli, JJ, Staines, A, Teras, LR, Thomas, T, Thompson, CA, Tinker, LF, Turner, J, Vajdic, CM, Vermeulen, RCH, Vijai, J, Villano, DJ, Vineis, P, Virtamo, J, Wang, SS, Wang, Z, Weiner, GJ, Witzig, TE, Wu, X, Ye, Y, Yeager, M, Zeleniuch-Jacquotte, A, Zhang, Y, Zheng, T   +101 more
core   +1 more source

Orbital mucosa-associated lymphoid tissue lymphoma

The Pan-American Journal of Ophthalmology, 2023
Orbital lymphomas are rare conditions, and most non-Hodgkin's lymphomas of the orbit are extranodal lymphomas of B cells of the marginal zone of the mucosa-associated lymphoid tissue type (MALT).
Lucas Pinheiro Machado Teles, Júlia Cristina De Oliveira Lima, Luiz Paulo Bastos Schmidt, Eric Pinheiro De Andrade   +3 more
doaj   +1 more source

La leucemia linfocítica crónica no es la única causa de linfocitosis persistente [PDF]

, 2008
La linfocitosis absoluta alerta sobre la posibilidad de malignidad hematológica y requiere investigar su causa. En el presente estudio analizamos de forma retrospectiva los datos de la citometría de flujo de muestras de sangre periférica de pacientes a ...
Cantú Rodríguez, Olga Graciela, Gutiérrez Aguirre, César Homero, Gómez Almaguer, David, Gómez Guijosa, Miguel Ángel, Méndez Ramírez, Nereida, Tarín Arzaga, Luz del Carmen   +5 more
core  

Primary Tracheal Malignant Lymphoma Detected during a Regular Checkup in an Asbestos Dust-Exposed Smoker [PDF]

, 2014
Primary tracheal malignant lymphoma is a rare disease;only 30 cases have been reported to date. A 73-year-old Japanese man with a history of asbestos exposure was undergoing biannual chest computed tomography (CT) twice a year as a routine procedure for ...
Kishimoto, Nobuyasu, Matsumura, Tadashi, Mizuno, Shoma, Ota, Seisuke, Shiomi, Kohei, Tanaka, Takehiro   +5 more
core   +1 more source

Interpretable CRAM‑Enhanced Lightweight Dual‑Branch CNN for Real‑Time Breast Cancer Histopathology in Internet‑of‑Medical‑Things Environments

Small, EarlyView.
This study presents an interpretable, lightweight hybrid deep learning model for real‐time analysis of breast cancer histopathology in IoMT‐enabled diagnostic systems. By integrating MobileNetV2 and EfficientNet‐B0 with a novel contextual recurrent attention module (CRAM), the framework achieves near‐perfect accuracy while providing transparent Grad ...
Roseline Oluwaseun Ogundokun, Rotimi‐Williams Bello, Pius Adewale Owolawi, Rytis Maskeliūnas, Abdulsatar Abduljabbar Sultan   +4 more
wiley   +1 more source

BCR and TLR signaling pathways are recurrently targeted by genetic changes in splenic marginal zone lymphomas

Haematologica, 2012
The genetics and pathogenesis of splenic marginal zone lymphoma are poorly understood. The lymphoma lacks chromosome translocation, and approximately 30% of cases are featured by 7q deletion, but the gene targeted by the deletion is unknown.
Qingguo Yan, Yuanxue Huang, A. James Watkins, Sylvia Kocialkowski, Naiyan Zeng, Rifat A. Hamoudi, Peter G. Isaacson, Laurence de Leval, Andrew Wotherspoon, Ming-Qing Du   +9 more
doaj   +1 more source