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Marine actinobacteria: perspectives, challenges, future directions
Antonie van Leeuwenhoek, 2005In this paper we evaluate the current state of research on the biology biotechnology of marine actinobacteria. The topics covered include the abundance, diversity, novelty and biogeographic distribution of marine actinobacteria, ecosystem function, bioprospecting, and a new approach to the exploration of actinobacterial taxonomic space.
Bull AT +3 more
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Marine actinobacteria: An important source of bioactive natural products
Environmental Toxicology and Pharmacology, 2014Marine environment is largely an untapped source for deriving actinobacteria, having potential to produce novel, bioactive natural products. Actinobacteria are the prolific producers of pharmaceutically active secondary metabolites, accounting for about 70% of the naturally derived compounds that are currently in clinical use.
Panchanathan, Manivasagan +5 more
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Estimating and comparing the diversity of marine actinobacteria
Antonie van Leeuwenhoek, 2005This paper reviews the application of species richness estimators to microbial diversity data and describes phylogenetic approaches to comparing microbial communities. The techniques are demonstrated using a community of marine actinobacteria. Results demonstrate that marine environments harbour massive actinobacterial diversity.
James E M, Stach, Alan T, Bull
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Marine actinobacteria: new opportunities for natural product search and discovery
Trends in Microbiology, 2007It is widely accepted that new drugs, especially antibiotics, are urgently required, and that the most propitious source remains natural products. We argue that in exploring new sources of bioactive natural products the marine environment warrants particular attention, in view of the remarkable diversity of microorganisms and metabolic products. Recent
Alan T, Bull, James E M, Stach
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Flavonoids from Marine-Derived Actinobacteria as Anticancer Drugs
Current Pharmaceutical Design, 2021Flavonoids represent a large diverse group of natural products that are used as a traditional medicine against various infectious diseases. They possess many biological activities including antimicrobial, antioxidant, anti-inflammatory, anti-cancer and anti-diabetic activities.
Wael N, Hozzein +5 more
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Novel actinobacteria from marine sponges
Antonie van Leeuwenhoek, 2005Actinobacteria exclusively within the sub-class Acidimicrobidae were shown by 16S rDNA community analysis to be major components of the bacterial community associated with two sponge species in the genus Xestospongia. Four groups of Actinobacteria were identified in Xestospongia spp., with three of these four groups being found in both Xestospongia ...
Naomi F, Montalvo +3 more
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Diversity and biogeography of marine actinobacteria
Current Opinion in Microbiology, 2006The actinomycetes, although not all the Actinobacteria, are easy to isolate from the marine environment. However, their ecological role in the marine ecosystem is largely neglected and various assumptions meant there was little incentive to isolate strains for search and discovery of new drugs.
Alan C, Ward, Nagamani, Bora
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Biologically active metabolites of marine actinobacteria
Russian Journal of Bioorganic Chemistry, 2010This review systematically data on the chemical structure and biological activity of metabolites of obligate and facultative marine actinobacteria, published from 2000 to 2007. We discuss some structural features of the five groups of metabolites related to macrolides and compounds containing lactone, quinone and diketopiperazine residues, cyclic ...
M P, Sobolevskaia, T A, Kuznetsova
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Extremozymes from Marine Actinobacteria
2016Marine microorganisms that have the possibility to survive in diverse conditions such as extreme temperature, pH, pressure, and salinity are known as extremophiles. They produce biocatalysts so named as extremozymes that are active and stable at extreme conditions. These enzymes have numerous industrial applications due to its distinct properties. Till
J, Suriya +4 more
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Production of Enzymes from Marine Actinobacteria
2016Marine actinobacteria are well recognized for their capabilities to produce valuable natural products, which have great potential for applications in medical, agricultural, and fine chemical industries. In addition to producing unique enzymes responsible for biosynthesis of natural products, many marine actinobacteria also produce hydrolytic enzymes ...
X Q, Zhao, X N, Xu, L Y, Chen
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