Results 11 to 20 of about 74,091 (305)

Marine Sponges as Pharmacy [PDF]

Marine Biotechnology, 2005
Marine sponges have been considered as a gold mine during the past 50 years, with respect to the diversity of their secondary metabolites. The biological effects of new metabolites from sponges have been reported in hundreds of scientific papers, and they are reviewed here.
Sipkema, D., Franssen, M.C.R., Osinga, R., Tramper, J., Wijffels, R.H.   +4 more
openaire   +2 more sources

Terpene biosynthesis in marine sponge animals. [PDF]

Proc Natl Acad Sci U S A, 2023
Sea sponges are the largest marine source of small-molecule natural products described to date. Sponge-derived molecules, such as the chemotherapeutic eribulin, the calcium-channel blocker manoalide, and antimalarial compound kalihinol A, are renowned for their impressive medicinal, chemical, and biological properties.
Wilson K, de Rond T, Burkhardt I, Steele TS, Schäfer RJB, Podell S, Allen EE, Moore BS.   +7 more
europepmc   +5 more sources

Kinase Inhibitors from Marine Sponges [PDF]

Marine Drugs, 2011
Protein kinases play a critical role in cell regulation and their deregulation is a contributing factor in an increasing list of diseases including cancer. Marine sponges have yielded over 70 novel compounds to date that exhibit significant inhibitory activity towards a range of protein kinases.
Skropeta, Danielle, Pastro, Natalie, Zivanovic, Ana   +2 more
openaire   +4 more sources

Some Like It Fat: Comparative Ultrastructure of the Embryo in Two Demosponges of the Genus Mycale (Order Poecilosclerida) from Antarctica and the Caribbean [PDF]

, 2015
0000-0002-7993-1523© 2015 Riesgo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License [4.0], which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
A Clarke, A Clarke, A Clarke, A Nørrevang, A Riesgo, A Riesgo, A Riesgo, AC Giese, AE Smith, AG Marsh, Ana Riesgo, Andrea Bertran, AR Pérez-Porro, AV Ereskovsky, AV Ereskovsky, B Waddell, B Waddell, C Cerrano, C Lévi, C Lévi, Conxita Avila, DA Pace, E Anderson, E Gaino, E Gaino, E Lepore, E Meroz, G Corriero, G Feller, G Kattner, GB Picken, H Boulekbache, H Heras, HV Wilson, HV Wilson, J Kowalke, James Bell, JB McClintock, JE Thompson, Joan Solà, JP Diaz, JR Pawlik, JS Pearse, JS Pearse, KH Sharp, KJ Eckelbarger, Laura Sánchez-Vila, LS Peck, LS Peck, M Maldonado, M Maldonado, M Maldonado, M Maldonado, M Maldonado, M Maldonado, M Sciscioli, M Sciscioli, M Sciscioli, M Wapstra, MF Gallissian, MJ Uriz, MS Hill, NL Bienati, NM Whiteley, O Kinne, O Maas, P Brien, PE Fell, PE Fell, PR Bergquist, PR Bergquist, PR Bergquist, R Borojevic, R Day, S Schmitt, S Taboada, Sergio Taboada, TF Goreau, TL Loh, TL Loh, TL Simpson, W Hagen, Y Delage, Y Watanabe   +83 more
core   +5 more sources

Florida’s Marine Sponges

EDIS, 2009
SGEF-169, a 4-page fact sheet by John Stevely and Don Sweat, describes why study and management of sponge populations remains essential to the health of Florida’s coastal waters and discusses their potential pharmaceutical value, harvesting practices, their history, biology, and other interesting facts.
John Stevely, Don Sweat
openaire   +6 more sources

A Soft Spot for Chemistry–Current Taxonomic and Evolutionary Implications of Sponge Secondary Metabolite Distribution

Marine Drugs, 2021
Marine sponges are the most prolific marine sources for discovery of novel bioactive compounds. Sponge secondary metabolites are sought-after for their potential in pharmaceutical applications, and in the past, they were also used as taxonomic markers ...
Adrian Galitz, Yoichi Nakao, Peter J. Schupp, Gert Wörheide, Dirk Erpenbeck   +4 more
doaj   +1 more source

Antibacterial Activity Ods Fractions of Marine Sponge Auletta SP. Against Mycobacterium Smegmatis [PDF]

, 2019
The marine sponge collected from tropical coral reefs in Manado North Sulawesi Indonesia was screened for antimicrobial activities. In the screening program to search for antituberculotic inhibitors, the result found that the ethanol extract ODS ...
Sumilat, D. A. (Deiske)
core   +2 more sources

Marine sponges as microbial fermenters. [PDF]

FEMS microbiology ecology, 2006
The discovery of phylogenetically complex, yet highly sponge-specific microbial communities in marine sponges, including novel lineages and even candidate phyla, came as a surprise. At the same time, unique research opportunities opened up, because the microorganisms of sponges are in many ways more accessible than those of seawater.
Hentschel, Ute, Usher, Kayley M., Taylor, Michael W.   +2 more
openaire   +4 more sources

RNA interference in marine and freshwater sponges [PDF]

, 2011
Background: The marine sponge Tethya wilhelma and the freshwater sponge Ephydatia muelleri are emerging model organisms to study evolution, gene regulation, development, and physiology in non-bilaterian animal systems. Thus far, functional methods (i.e.,
Cieniewicz, Brandon, Danka, Elizabeth S., Haen, Karri M., Hammel, Jörg U., Hill, April L., Hill, Malcolm S., Knight, Scott W., Lavrov, Dennis V., Nickel, Michael, Posfai, Dora, Rivera, Ajna S., Winters, Ian P., Wörheide, Gert   +12 more
core   +1 more source

Hiding in plain sight: the globally distributed bacterial candidate phylum PAUC34f [PDF]

, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Chen, M. L., Becraft, E. D., Pachiadaki, M., Brown, J. M., Jarett, J. K., Gasol, J. M., Ravin, N.
Becraft, Eric D., Brown, Julia M., Chen, Michael L., Gasol, Josep M., Herndl, Gerhard J., Jarett, Jessica K., Moser, Duane P., Nunoura, Takuro, Pachiadaki, Maria G., Ravin, Nikolai V., Stepanauskas, Ramunas, Woyke, Tanja   +11 more
core   +2 more sources