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Marine Sponges as Pharmacy [PDF]
Marine sponges have been considered as a gold mine during the past 50 years, with respect to the diversity of their secondary metabolites. The biological effects of new metabolites from sponges have been reported in hundreds of scientific papers, and they are reviewed here.
Sipkema, D. +4 more
openaire +2 more sources
Promising antiparasitic agents from marine sponges. [PDF]
Parasitic diseases especially those prevail in tropical and subtropical regions severely threaten the lives of people due to available drugs found to be ineffective as several resistant strains have been emerged. Due to the complexity of the marine environment, researchers considered it as a new field to search for compounds with therapeutic efficacy ...
Mostafa O, Al-Shehri M, Moustafa M.
europepmc +3 more sources
Kinase Inhibitors from Marine Sponges [PDF]
Protein kinases play a critical role in cell regulation and their deregulation is a contributing factor in an increasing list of diseases including cancer. Marine sponges have yielded over 70 novel compounds to date that exhibit significant inhibitory activity towards a range of protein kinases.
Skropeta, Danielle +2 more
openaire +4 more sources
Terpene biosynthesis in marine sponge animals [PDF]
Sea sponges are the largest marine source of small-molecule natural products described to date. Sponge-derived molecules, such as the chemotherapeutic eribulin, the calcium-channel blocker manoalide, and antimalarial compound kalihinol A, are renowned for their impressive medicinal, chemical, and biological properties.
Kayla Wilson +7 more
openaire +3 more sources
RNA interference in marine and freshwater sponges [PDF]
Background: The marine sponge Tethya wilhelma and the freshwater sponge Ephydatia muelleri are emerging model organisms to study evolution, gene regulation, development, and physiology in non-bilaterian animal systems. Thus far, functional methods (i.e.,
Cieniewicz, Brandon +12 more
core +1 more source
Marine sponges as microbial fermenters. [PDF]
The discovery of phylogenetically complex, yet highly sponge-specific microbial communities in marine sponges, including novel lineages and even candidate phyla, came as a surprise. At the same time, unique research opportunities opened up, because the microorganisms of sponges are in many ways more accessible than those of seawater.
Hentschel, Ute +2 more
openaire +4 more sources
Diversity of sponges and their microbial composition derived from marine lake: An overview [PDF]
Marine lakes are landlocked marine water bodies isolated from the surrounding marine environment. Sponges have been found to be one of the predominant benthic taxa found in marine lakes.
Puspitasari Kayla F. +4 more
doaj +1 more source
Patterns of Sponge Abundance Across a Gradient of Habitat Quality in the Wakatobi Marine National Park, Indonesia [PDF]
Sponges are important components of reef communities worldwide, fulfilling a number of important functional roles. Habitat degradation caused by the loss of hard corals has the potential to cause increases in sponge abundance and percentage cover as they
Bell, JJ +3 more
core +1 more source
Genomic blueprints of sponge-prokaryote symbiosis are shared by low abundant and cultivatable Alphaproteobacteria [PDF]
Marine sponges are early-branching, filter-feeding metazoans that usually host complex microbiomes comprised of several, currently uncultivatable symbiotic lineages.
Cox, Cymon +6 more
core +4 more sources
Interaction Mechanisms Between Marine Sponges (Porifera) and Microplastics: A Bioecological Overview [PDF]
Microplastics, plastic particles measuring less than 5 mm, have become one of the main pollutants in marine ecosystems, with significant impacts on marine organisms, including sponges.
Hombing Angelina Br +5 more
doaj +1 more source

